ocr: Question Endponnts Does drug "a" result in tumor regression? Regression in measurable disease Radionuclide bone scan changes Changes in a biochemical marker Posttherapy decline in PSA or acid phosphatase Does drug "b" delay progression? Time to progression Rise in PSA Growth of existing lesions Prevention of new lesions New symptoms of disease Does drug "c" improve quality of life? Functional indices Pain relief or change in analgesic With or without concomitant measures of tumor regression Does drug "d" delay the time tO which a Tumor progression change in therapy 15 required? Tumor progressi ...
