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Graphics Interchange Format  |  1999-06-07  |  113.8 KB  |  751x453  |  8-bit (240 colors)
   ocr: TABLE 32.9-4. Phase III Trials of Chemotherapy Plus Radiation in Anal Cancer Colostomy- Radiation Evaluable Local Free Overall Study Arms Chemotherapy Dose Patients Failure Survival Survival INTERGROUP RTOG/ECOG)" Radiation + 5-FU 5-FU: 1000 mg/m", infusion d 4500 cGy 145 36% 59% 67% 1-4, wk 1 and 4 Radiation + 5-FU: 1000 mg/m?, infusion d 4500 cGy 146 18%, 71%, 76% 5-FU-mit C 1-4, wk 1 and 4 (P=. .001) (P . .019) P =.18] Mit C: 10 mg/m", d 1 and 29 EORTCSL.143 Radiation alone 4500 cGy, boost 69% 22% 1500-2000 cGy* 103, total Radiation + 5-FU: 750 mg/m, infusion d 4500 cGy, boost 42% (sig.) 41 ...