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Cancer - Principles & Practice of Oncology
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Oncology.iso
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PPO
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CHAP19
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T7_4.GIF
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1999-06-07
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68.5 KB
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Pharmacokinetic Parameters Etoposide Teniposide Vdss (L/m?) 6.7-12.6 3-16 % Unbound 6-8* (up to 40i in 0.44-1.25* (over 2 patients with 1n patients with hypoalbuminemia and hypoalbuminemia) hyperbilirubinemia) Terminal half-life (h) 4.1-11.0 5.2-13.9 Cl, (ml/min/m-) 17.7-31.8 9.4-15.4 Cl, (ml/min/m-) 3.4-7.4 0.97 Clr (ml/min/m-) 10.3-28.4 8.4-14.4