ocr: TABLE 18-3. (Continued) Molecular Weight Interleukin (kd)* Biologic Efects References IL-12 75 (heterodimer of Stimulates antigen-activated CD4+ and CD8 + Tcells (independent of 58-61 40 and 35 IL-2); synergizes with IL-2 in induction of CIL and additive with IL- subunits) 2andCTL.proliferation: enhances NK: activity; stimulates IFN-ysecre- tion by resting and activated human PBLS IL-13 132aa Induces prolileration and diflerentiation of human B cells activated by CD40 ligand; induces IgE synthesis; enhances expression of CD23/Fc epsilon RII and class II MHC antigens on resting B cells IL-14 46 ...
