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   ocr: TABLE 18-21. Toxicity Associated with the Administration of High-Dose Interleukin-2 Alone in 447 Consecutive Treatment Courses* Calegory Toxicily (% of Courses) Systemic Malaiset (14.5), chillst (18.3), pruritust (8.9), weight gain >5% body weight (70.9), edema causing neurovascular compression (0.9) Hemodynamic Hypotension requiring pressors (52.1) Cardiac Arrhythma (6.5), angina (1.1), myocardial infarction (0.4) Pulmonary Respiratory distress (4.0), intubation (2.9), pleural effusion requiring thoracentesis (1.1) Renal Oliguria (26.1), elevated creatinine (2.1-6 mg/dl. = 62; >6 mg/dl. = 6.3 ...