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Cancer - Principles & Practice of Oncology
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T20.GIF
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1999-06-07
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TABLE 18-20. Administration of IL-2 as an Intravenous Bolus for the Treatment of l'atients with Metastatic Melanoma instatution/Author Year Dose Regimen (per Cycle) N CR PR XCR + PR Parkinson-" (Cetus)" 1990 600,000 IU/kg tid X 5 days 46 2 8 22 Demchak273 (Cetus)" 1993 600,000 IU/kg tid X 5 days 27 0 4 26 Rosenberg"6 (Cetus) 1994 720,000 1U/kg tid X 5 days 134 10 13 17 Hersh-" (Cetus)' 1989 001-14 MU/m? daily dose 26 0 3 12 Budd278 (HLR) 1990 1-22 MIU/m? daily dose 23 0 5 22 Whitehead7 (Cetus) 1991 36-60 MIU/m daily dose 12 0 4 10 Sparano-o (HLR)* 1993 6 MU/m tid X 5 days 14 0 2 5 Total 342 12 ...