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1992-12-06
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Biotin
U.S. Recommended Daily Allowances
Infants Children Adults and Pregnant or
(0-12 mo.) (1-3 years) Children 4 Years + Nursing Women
50 micrograms 150 mcg 300 mcg 300 mcg
(The U.S. RDA amounts are sufficient to meet the needs
of practically all healthy people. FDA set these based on
the 1968 Recommended Dietary Allowances by the National
Research Council of the National Academy of Sciences.
However, in 1989, the council lowered its ranges of safe
and adequate daily dietary intakes for biotin to 10 to 15
micrograms for infants, 20 to 30 mcg for children, and 30
to 100 mcg for adults. FDA is in the process of revising
its U.S. RDAs.)
Biotin is a sulfur-containing, B-complex vitamin found
in foods and produced by microorganisms in the lower
gastrointestinal tract.
Functions: Activates certain enzymes that aid in
metabolism of carbon dioxide; involved in metabolism of
protein, fats and carbohydrates.
Sources: Widely distributed in foods that are sources
of B vitamins, including cereal-grain products, liver, egg
yolk, soy flour, and yeast.
Deficiency: Signs include loss of appetite, nausea,
vomitting, inflammation of the tongue, pallor, depression,
hair loss, and dry, scaly skin. Some rare biotin-related
inborn errors of metabolism may cause deficiency;
otherwise, deficiency is extremely rare in the United
States.
Excess: No effects have been reported.