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1994-08-27
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Document 0720
DOCN M9480720
TI [A case of adult T cell leukemia complicated with strongyloidiasis and
amplification of pneumocystis carinii DNA in bronchoalveolar lavage
fluid]
DT 9410
AU Adachi N; Ohta K; Negoro N; Kurihara N; Takeda T; First Department of
Internal Medicine, Osaka City University; Medical School, Japan.
SO Nippon Kyobu Shikkan Gakkai Zasshi. 1994 Apr;32(4):348-52. Unique
Identifier : AIDSLINE MED/94315792
AB The patient was a 75-year-old male, who simultaneously showed symptoms
of bacterial meningitis during steroid treatment for erythroderma and
symptoms of respiratory failure. Based on ground-glass shadows in both
lungs on chest X ray, bronchoalveolar lavage (BAL) was carried out and
strongyloides was detected. In addition to strongyloidiasis, the patient
was shown to have the complication of pneumocystis carinii (PC)
pneumonia after PC DNA was detected in BAL fluid using a PCR assay. When
other causes for immunodeficiency affecting the incidence of
opportunistic infection were investigated, the ATL virus was detected in
peripheral blood cells and monoclonal amplification was indicated,
though the presence of anti-ATL antibody was negative. According to the
results, this patient was found to have early stage adult T cell
leukemia. In conclusion, we treated this adult T cell leukemia patient
who had strongyloidiasis and amplification of PC DNA in BAL and for
which the PCR assay, a new technology used for diagnosing PC pneumonia,
was considered to be effective.
DE Aged *Bronchoalveolar Lavage Fluid/PARASITOLOGY Case Report DNA,
Fungal/*ANALYSIS English Abstract Human Leukemia,
T-Cell/*COMPLICATIONS Lung Diseases, Parasitic/*DIAGNOSIS Male
Opportunistic Infections/*DIAGNOSIS Pneumonia, Pneumocystis
carinii/*DIAGNOSIS Polymerase Chain Reaction
Strongyloidiasis/*DIAGNOSIS JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).