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- *******************************************
- * Plant lipid transfer proteins signature *
- *******************************************
-
- Plant cells contain proteins, called lipid transfer proteins (LTP) [1,2,3],
- which are able to facilitate the transfer of phospholipids and other lipids
- across membranes. These proteins, whose subcellular location is not yet known,
- could play a major role in membrane biogenesis by conveying phospholipids from
- their site of biosynthesis to membranes unable to form these lipids.
-
- Plant LTP's are proteins of about 9 Kd (90 amino acids) which contain eight
- conserved cysteine residues all involved in disulfide bridges, as shown in
- the following schematic representation.
-
- +-----------------------+
- | +------+ |
- | | | | ****************
- xCxxxxCxxxxxxCCxxxxxxxxCxCxxxxxxxxxxxCxxxxxxCxx
- | | | |
- +--------|-------------+ |
- +--------------------+
-
- 'C': conserved cysteine involved in a disulfide bond.
- '*': position of the pattern.
-
- -Consensus pattern: [LIVM]-P-x(2)-C-x-[LIVM]-x-[LIVM]-x-[LIVMFY]-x-[LIVM]-S-
- x(3)-[DN]-C-x(2)-[LIVM]
- [The two C's are involved in disulfide bonds]
- -Sequences known to belong to this class detected by the pattern: ALL.
- -Other sequence(s) detected in SWISS-PROT: NONE.
-
- -Note: some of these proteins were originally thought to be alpha-amylase/
- protease inhibitors (PAPI).
-
- -Last update: December 1992 / Text revised.
-
- [ 1] Wirtz K.W.A.
- Annu. Rev. Biochem. 60:73-99(1991).
- [ 2] Arondel V., Kader J.C.
- Experientia 46:579-585(1990).
- [ 3] Ohlrogge J.B., Browse J., Somerville C.R.
- Biochim. Biophys. Acta 1082:1-26(1991).
-