Changing the size and appearance of point entities affects all point entities already in the drawing, as well as all points that you subsequently draw. Positive values represent the absolute size of the point entity measured in drawing units. Negative values represent a percentage relative to the drawing screen, so that points retain their visual size as you use the Zoom command to change the magnification of the drawing.
When you regenerate the drawing, all point entities change to reflect the new size and appearance settings.