malaria pills for a year?

This topic was created by sirena
[Fri 7 May, 14:56 Tasmanian Standard Time]

I'm planning to spend 8-12 months in Africa, and all the
countries I want to visit have high malaria risk. What have
you African travellers done about this problem? Taking the
anti-malaria pills (I have Lariam) for too long is
dangerous, and not taking them regularly is
dangerous...should I just take them in extremely risky
places?

[There are 21 posts - the latest was added on Tue 25 May, 5:26]

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  1. You better take them Added by: Kevin
    [Timestamp: Fri 7 May, 17:01 Tasmanian Standard Time]

    I have been to Africa three times.
    I am leaving for Kenya in two weeks from now.
    You better take the malaria pills. I know travelers who
    died of malaria because they had the same concerns as your
    and they refused to take their pills. Apparently they got
    hit by the disease.
    Good Luck



  2. take the damn pills! Added by: william (slothtec@global.co.za)
    [Timestamp: Fri 7 May, 20:34 Tasmanian Standard Time]

    http://www.backpackafrica.com/malaria_info.html
    is probably what you should be reading....
    Before I'd read these pages, I'd never heard of side
    effects from the pills...possibly someone can quote from
    the packaging? (I've never experienced any, except on one
    occasion when I took too many!)



  3. Lariam Added by: Dan (exet0407@sable.ox.ac.uk)
    [Timestamp: Fri 7 May, 21:13 Tasmanian Standard Time]

    I was in Africa for 8 weeks and took Lariam the whole time,
    it didn't affect me at all. But some people in our group
    complained of not sleeping, palpitations etc.
    Basically if they don't affect you I would definitely take
    them, so its worth trying them for a couple of weeks and
    seeing if you have any side effects.
    You have to remember that they can take up to four weeks to
    kill the malaria, so you can't just take Lariam in high-risk
    countries and something else as soon as you move out of the
    high-risk area.
    The best advice is just to not get bitten! Get a really good
    net (& a sewing kit to fix any tears in it) and some really
    nasty strong deet repellent.
    Good luck!



  4. take them Added by: pieter
    [Timestamp: Fri 7 May, 21:14 Tasmanian Standard Time]

    i was told to take larium not longer than 3 months orso, and
    then switch to anoter one, there is one to take everyday,
    unfortunately i forgot the name
    have fun pieter



  5. A balance Added by: Tramper
    [Timestamp: Fri 7 May, 21:40 Tasmanian Standard Time]

    On my trip, I was away for a year, leaving Morocco in Oct
    and arriving RSA in the following Sept. We didn't take the
    tablets until Mauritania, giving a week or so to build up
    resistance before meeting the first mossies in Mali
    (Bamako), we then took the tablets from then (Nov) until
    arriving in Uganda (March). In East Africa we had a break
    as the combination of dry season and altitude, reduced the
    number of mossies (hardly saw any). We took then again for
    Lake Malawi (week before, followed by four weeks after) and
    then stopped through Zim, Bots, Nam and RSA.
    This was a concious balance between the long term risk of
    chloroquine/paludrine and malaria. Basically we tried to
    follow the local ex-pats in each area. If you are
    travelling in the wet season, then the risk of malaria is
    much higher, so take the tablets. Our route folowed the dry
    season, partly for malaria risk, but also the climate is
    more comfortable.
    Finally, as always, you only get malaria if you get bitten,
    so protection is best. Cover up when the sun goes down, and
    use a repellant.



  6. Once a week or everday Added by: Anon
    [Timestamp: Fri 7 May, 23:19 Tasmanian Standard Time]

    I just picked up my Larium pills and it states that it
    should be taken once a week. i though it was everday. Is
    this correct?



  7. Big mistake... Added by: Dan
    [Timestamp: Sat 8 May, 1:07 Tasmanian Standard Time]

    Ohhhh no, every week is right. Take 'em every day and they
    mess with your head, man.



  8. watch your liver Added by: kitwe
    [Timestamp: Sat 8 May, 1:59 Tasmanian Standard Time]

    Sirena
    I've worked in a high-risk malarial area (Zambia) for a
    couple of years, and in my experience it is not wise to take
    anti-malarials for extended periods of time.
    I wasn't on Larium but dyoxy though essentially they both
    damage your liver. I ended up stopping during the dry season
    - not that it helped, cause I ended up getting it anyhow...



  9. Be careful Added by: Rob (martin_r@hotmail.com)
    [Timestamp: Sat 8 May, 4:33 Tasmanian Standard Time]

    I took Larium for a year when I was in Kenya, on the advise
    of my doctor. Most doctors are clueless when it comes to
    malaria or tropical diseases. They open a book and say,
    "hmmm...well, it says that you can get malaria in this
    country so you'd better take the medication." I had a
    discussion with a doctor in Kenya after about six months
    there (and a dislocated shoulder in a car accident), and he
    nearly passed out when I told him I was told to take the
    medication for the year I was there. It was my first time
    abroad, and I was young and naive, and probably should have
    done more homework on this issue. I didn't notice anything
    really bad there but my hair would fall out (faster than it
    usully does!!;>)). I did have a grand mal seizure a year
    later, and I was always curious as to whether the
    medication I took had anything to do with it. They did all
    these tests and didn't find anything. I haven't had one
    since and I feel fine today. I'm thinking of returning to
    Africa next year and I'm a bit concerned about what to do.
    Any advice on countries I could go to where malaria is not
    a big problem? I'd prefer not to take the damn pills.
    Sirena, you should take this issue up with a doctor who has
    more insight into malaria and these kinds of illnesses,
    diseases, etc. Good luck.



  10. Long-term anti-malarials Added by: Gerry (gerryar@sprint.ca)
    [Timestamp: Sat 8 May, 8:12 Tasmanian Standard Time]

    I agree with Tramper and Rob. If you can, speak to a
    tropical disease specialist about the long-term effects of
    anti-malarials; talk to travellers; talk to the expats who
    are living in the countries you're visiting; and even look
    through a pharmaceutical book to check on the drugs and
    their side-effects. However, the pros and cons of which
    anti-malarials to take or in fact whether to take one at
    all, is a never-ending topic of conversation and there
    seems to be no definite concensus except to make your own
    educated decision based on your own experiences and the
    malarial conditions in the country you're visiting. As an
    expat in Nigeria (4 yrs) and Uganda (3 years) and after
    many visits to East Africa there seem to be two issues:
    whether or not to take any anti-malarials in the first
    place (or just use better protection measures and then have
    blood samples taken at the first sign of illness); and the
    second issue is, if you decide to take anti-malarials then
    which one for a long-term stint? Larium is not recommended
    for long-term use as far as I know - however it is the drug
    of choice for short-term by most doctors I have dealt
    with. Usually for long-term a combination of drugs is
    recommended, such as Chloroquine (weekly) and Paludrine
    (daily), but there can still be side-effects as with any
    medication taken. If you only take anti-malarials in the
    'risky' areas you may not be covered as malaria can take
    several weeks to develop, which is why it's recommended to
    take anti-malarials for one month after returning from a
    malarial zone. It's not an easy call to make and once
    you're in Africa you may decide to switch, which is what
    many expats seem to do. I took Larium for a couple of
    months, switched to Chloroquine and Paludrine, then stopped
    completely for the last year and I was malaria-free.
    However, during a 2 month stay last year with no anti-
    malarials, I did have malaria but very mild as it was
    caught early on. Whatever you decide I hope all goes well
    for you and that you have a great time.



  11. Mefloquine Added by: kudu
    [Timestamp: Sat 8 May, 14:10 Tasmanian Standard Time]

    The US Peace Corps issue mefloquine as standard procedure.
    I took em for 2 years--no side effects, no malaria. A few
    in my group stopped; some complained of nightmares--I'm not
    convinced it's solely due to the drug, considering you're
    exposed to an entirely strange new environment all of a
    sudden.



  12. Mefloquine Added by: Toodles
    [Timestamp: Sat 8 May, 16:24 Tasmanian Standard Time]

    Speak to any peace corp volunteer... most were on malaria
    meds for two years.... they should help your peace of mind
    or confirm your fears... good luck



  13. larium Added by: Bill and Ben
    [Timestamp: Sat 8 May, 21:33 Tasmanian Standard Time]

    We know some PCV's. They were surprised to find that it
    should not be taken for more than three months. This is the
    manufacturers reccomendation.
    We have seen many people with bad side effects. Ben was
    almost hospitalised in Eritrea with the side effects.
    Seriously.
    The side effects can be lessened by taking half a tablet
    twice a week.



  14. read tramper Added by: Michael (danea@vip.cybercity.dk)
    [Timestamp: Sun 9 May, 1:53 Tasmanian Standard Time]

    Hi Sirena,'
    Lsten to tramper,
    Staying different parts of Africa for longer periods
    I recommend
    to be aware of mosquitoes and
    to protect ourself especially in the evening wear long
    clothes and staying behind mosquitonets after one hour
    before sunset (6 p.m.)
    Profylaxis is no guarantee against malaria but will make
    detection (laboratory) more difficult when taken.
    Therefore use mosquit spells on nude areas on the body in
    the eveninbg !
    Regards



  15. Go to a tropical disease centre. Added by: xs
    [Timestamp: Mon 10 May, 14:38 Tasmanian Standard Time]

    Go to someone who knows. Larium given to the wrong person
    can be disasterous. There are ten questions about yourself
    which need to be answered (are you paranoid, depressive,
    etc) to judge if you should take it. It should not be taken
    more than 3 months anyway. It can be used as a cure (ie
    after infection) - ask an expert for detials. Concentrate
    more on prevention of bites than anything.
    If you do get malaria, the most important thing is to keep
    your temperature down (ice, water, anything). Do not hold
    back because 99% of the time it is the high temperature
    that cooks your brain and kills.
    Don't be paranoid about getting malaria, be paranoid about
    not getting bitten.
    Have fun



  16. loopy larium Added by: mosi
    [Timestamp: Tue 11 May, 1:08 Tasmanian Standard Time]

    but don't you love those bizarre dreams when you take
    larium ?
    I kinda miss my weekly visits from the 'larium girls' now
    that I'm back home...



  17. Your call Added by: WT
    [Timestamp: Tue 11 May, 15:00 Tasmanian Standard Time]

    Malaria kills. I found myself in a hospital after being
    unconscious for 3 days. I also have taken Chloroquinine for
    years, and Larium for weeks at a time. Do your own
    research. Expect conflicting opinions from "professionals"
    and lots of anectdotal stories from travelers.
    ~
    Be aware of the need, types of misquitoes, the risks,
    prevention, the treatments, and the symptoms of both
    malaria and various "side-effects." Remember, when
    traveling many places, you gotta haul your own ass out. You
    must be as aware as possible, and then symply use your own
    best judgment, based on the best information.
    ~
    Try CDC and IAMAT for some excellent information. They are
    on the net. Search: "Malaria" etc.
    ~



  18. Prevention doesn't always work... Added by: Ken (ken27@dynamite.com.au)
    [Timestamp: Tue 11 May, 22:35 Tasmanian Standard Time]

    You can take every precaution under the sun and the hallowed
    advice of every tropical disease specialist and travel-weary
    person out there. But if that anopheles mossie gets you and
    the fever starts to kick in, and you happen to be a few
    thousand miles from the nearest decent medical facility, you
    better have a self-test kit and treatment dose of drugs
    handy. There are many options, ask your specialist about
    them.



  19. Lariam Ills Added by: Jess
    [Timestamp: Wed 12 May, 1:37 Tasmanian Standard Time]

    I agree with everyone that if you are going to a high
    malarial region, it is important to use caution and take
    some sort of prophylaxis. Howevere, in my own experiences..
    Went to kenya for three weeks, took larium, no problem. Two
    years later, went back for 6 months, took larium...
    Major problems... The typical nightmares (which are so vivid
    and distressing I don't think they can be called typical - I
    actually thought I had shot my mother in the head at one
    point and it took a friend to calm me down and tell me it
    was a dream, even though my mom was in DC, Not anywhere near
    Nairobi!), weird mental experinces during the day, a
    decreased torerance for stress, many 'ugh' more...
    The problems I was experiencing were so distressing and
    lifestyle-inhibiting that I decided I'd rather get malaria
    than continue on with Larium. I eventually took some other
    more mild anti-malarial and was ok with that, But when asked
    by anyone about Larium, I am adamently opposed to it.
    Upon return to the states a mild form of the symptoms
    continued, especially the dreams, and I am still affected 4
    years later. There are many studies that have been done and
    it is known that anyone with any history of psychological
    problems (especially familial depression or schizo.) should
    not take Larium.
    Do research. Protect yourself from the disease and the
    drug!!!



  20. Going my way? Added by: Microkid
    [Timestamp: Tue 25 May, 3:47 Tasmanian Standard Time]

    I read ALOT about Larium versus other meds as I'm going to
    high risk areas for 3 months. Here's some snippets :
    I spoke to ex-pats who'd lived in Zim for years and they
    thought initally I was going too long to be on Larium. But
    also took into account that I would be travelling in and out
    if low and high velt as they called it, so perhaps it was
    necessary. They had all taken a local drug called DeltaPrim
    which might be worth checking out (aka Maloprim).
    Larium is also used as a treatment and some east african
    doctors do not like westerners on Larium as they fear that
    the malaria will become resistent to it and they will have
    one less treatment and alot more problems.
    Larium is not widly known in west africa and Mefloquinine
    intolerance (unable to take Larium because of severe side
    effects) is often confused with Malaria.
    From talking to people I have a theory that what you intend
    to be doing/your state of mind and security affects your
    reaction to Larium. People in stable environments like
    voluntary workers tend to have mild side effects, whereas
    many independant travellers on the move all the time and in
    new surroundings feel edgy, paraniod and generally "not
    themselves".
    No widescale study of tourist populations taking larium has
    been carried out. Most studies have been on male miltary
    personnel. More vicious side effects have been reported in
    'slight' people ie under 50kgs. There is only one available
    dose of Larium regardless of build.
    Alcohol has also been a factor in side effects, you are
    recommended not to drink 24 hrs before and after your
    weekely dose.
    Dioxy is not a good idea for women as its an antibiotic and
    so can cause yeast infections (ouch!) and it makes you
    sun sensitive.
    What I'm doing:
    taking lariumm for a month before I go (4 tabs) and will
    continue with it if I have no very bad effects. The no
    drinking will be difficult for a irish person though!! ;-)
    My advice:
    Unless you drink very heavily, are a small person or have a
    history of depression/mental illness try Larium first. Take
    Choroquine and Pauldrine if larium doesn't work for you.
    Think carefully about larium if you are travelling
    independantly (I'm going with a tour group)
    good luck!



  21. malaria is better than the pills Added by: pam
    [Timestamp: Tue 25 May, 5:26 Tasmanian Standard Time]

    Do not take lariam for longer than 2 months. The side effects are too bad and it hurts your liver. I would not take them at all but carry them around. As soon as you think you have malaria take the pills or go to a medical assitant who are all over. That┤s the way the South Africans do it as well




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