$Unique_ID{BRK03259} $Pretitle{} $Title{omeprazole} $Subject{Prilosec MSD Gastric acid secretion inhibitor omeprazole peptic ulcer disease gastroesophageal reflux hypersecretory syndromes acid stomach} $Volume{} $Log{ Prilosec*0325901.scf} Copyright (C) 1993 Publications International, Ltd. omeprazole ------------------------------------------------------------------------------ BRAND NAME (Manufacturer) Prilosec (MSD) TYPE OF DRUG Gastric acid secretion inhibitor INGREDIENT omeprazole DOSAGE FORM Delayed-release capsules (20 mg) STORAGE Omeprazole should be stored at room temperature in a tightly closed container. USES Omeprazole is prescribed to treat peptic ulcer disease, gastroesophageal reflux, and hypersecretory syndromes. This drug suppresses the secretion of acid in the stomach. TREATMENT Omeprazole capsules should not be opened, chewed, or crushed. They should be taken with a glass of water on an empty stomach. It is best to take the dose one hour before meals or two hours after meals. Try to take the medication at the same time(s) each day. If you miss a dose of the medication, take the missed dose as soon as possible, then return to your regular dosing schedule. If it is almost time for the next dose, however, skip the one you missed and return to your regular schedule. Do not double the next dose (unless your doctor directs you to do so) of the medication. It is important that you take this medication for as long as prescribed by your doctor. SIDE EFFECTS Minor. Abdominal pain, burning sensation in mouth, constipation, diarrhea, dizziness, dry mouth, fatigue, headache, or palpitations. To relieve constipation while you are being treated with this medication, exercise and drink more water, unless your doctor directs you to do otherwise. To avoid dizziness when you stand, contract and relax the muscles of your legs for a few moments before rising. Do this by pushing one foot against the floor while raising the other foot slightly, alternating feet so that you are "pumping" your legs in a pedaling motion. To relieve dry mouth, chew sugarless gum or suck on ice chips or a piece of hard candy. Major. Tell your doctor about any side effects that are persistent or particularly bothersome. IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about itching, numbness or tingling of fingers or toes, rash, or yellowing of the eyes and skin. INTERACTIONS Omeprazole may increase the effects of diazepam, warfarin, and phenytoin. Be sure to tell your doctor about any medications you are currently taking, especially any of the ones listed above. WARNINGS * Be sure to tell your doctor about unusual reactions you have had to any drugs, especially to omeprazole. * Tell your doctor if you have ever had thyroid disease, liver disease, Addison's disease, or Cushing's disease. * This medication may cause dizziness and light-headedness, so use caution while driving a car or operating potentially dangerous equipment. * Long-term and high-dose treatment with omeprazole has been associated with higher incidences of gastric tumors. Consult your doctor if you need to take high doses of omeprazole for a long time. * Be sure to tell your doctor if you are pregnant. Adequate human studies have not been conducted with omeprazole. Also, be sure to tell your doctor if you are breast-feeding an infant. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.