$Unique_ID{BRK03215} $Pretitle{} $Title{medroxyprogesterone} $Subject{Amen Carnrick Curretab Reid-Provident Cycrin Ayerst acetate Provera Upjohn Progesterone medroxyprogesterone female hormone abnormal menstrual bleeding menstruation} $Volume{} $Log{ Provera 2.5 mg*0321501.scf Provera 10 mg*0321502.scf} Copyright (C) 1993 Publications International, Ltd. medroxyprogesterone ------------------------------------------------------------------------------ BRAND NAMES (Manufacturers) Amen (Carnrick) Curretab (Reid-Provident) Cycrin (Ayerst) medroxyprogesterone acetate (various manufacturers) Provera (Upjohn) TYPE OF DRUG Progesterone INGREDIENT medroxyprogesterone DOSAGE FORM Tablets (2.5 mg, 5 mg, and 10 mg) STORAGE These tablets should be stored at room temperature in a tightly closed container. USES Medroxyprogesterone is a synthetic progesterone (progesterone is a female hormone that is naturally produced by the body) that is used to treat abnormal menstrual bleeding, difficult menstruation, or lack of menstruation. It can be used for other conditions as determined by your doctor. TREATMENT This medication may cause stomach irritation. To avoid or minimize this side effect, you can take medroxyprogesterone with food or immediately after a meal. If you miss a dose of this medication, take the missed dose as soon as possible, unless it is almost time for the next dose. In that case, do not take the missed dose at all; just return to your regular dosing schedule. Do not double the next dose of the medication. SIDE EFFECTS Minor. Acne, dizziness, hair growth, headache, nausea, or vomiting. These side effects should disappear as your body adjusts to the medication. This medication can increase your sensitivity to sunlight. Avoid prolonged exposure to sunlight and sunlamps. Wear protective clothing and use an effective sunscreen. This medication may cause tenderness, swelling, or bleeding of the gums. Brushing and flossing your teeth regularly may prevent this. Also, you should see your dentist regularly while you are taking this medicine. If you feel dizzy or light-headed, sit or lie down for a while; get up slowly from a sitting or reclining position, and be careful on stairs. Major. Tell your doctor about any side effects that are persistent or particularly bothersome. IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about breast tenderness; change in menstrual patterns; chest pain; depression; fainting; hair loss; itching; pain in the calves; rapid weight gain (three to five pounds within a week); rash; slurred speech; sudden, severe headache; swelling of the feet or ankles; unusual vaginal bleeding; or yellowing of the eyes or skin. INTERACTIONS Medroxyprogesterone should not interact with other medications if it is used according to directions. WARNINGS * Tell your doctor about unusual or allergic reactions you have had to any medications, especially to medroxyprogesterone, progestin, or progesterone. * Before starting this drug, tell your doctor if you have ever had cancer of the breast or genitals, clotting disorders, diabetes mellitus, depression, epilepsy, gallbladder disease, asthma, heart disease, kidney disease, liver disease, migraines, porphyria, stroke, or vaginal bleeding. * A package insert should come with this drug. Read it carefully, and ask your doctor if you have any questions. * If this drug makes you dizzy or drowsy, do not take part in any activities that require alertness, such as driving a car or operating potentially dangerous machinery. * Be sure to tell your doctor if you are pregnant. Medroxyprogesterone should not be used during the first four months of pregnancy because it has been shown to cause birth defects. Since hormones have long-term effects on the body, medroxyprogesterone should be stopped at least three months before you attempt to become pregnant. Also, tell your doctor if you are breast-feeding an infant. Small amounts of medroxyprogesterone pass into breast milk. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.