$Unique_ID{BRK03188} $Pretitle{} $Title{ibuprofen} $Subject{Aches-N-Pain Lederle Advil Whitehall Children Genpril Goldline Haltran Roberts Ibuprin Thompson Medical Medipren McNeil CPC Midol 200 Glenbrook Motrin Upjohn Motrin IB Nuprin Bristol-Myers Pamprin-IB Chattem PediaProfen McNeil CPC Rufen Boots Trendar Whitehall Nonsteroidal anti-inflammatory analgesic ibuprofen inflammation pain swelling stiffness arthritis gout bursitis tendinitis painful menstruation body chemicals prostaglandins} $Volume{} $Log{ Motrin 300 mg*0318801.scf Motrin 400 mg*0318802.scf Motrin 600 mg*0318803.scf Rufen 400 mg*0318804.scf Rufen 600 mg*0318805.scf} Copyright (C) 1993 Publications International, Ltd. ibuprofen ------------------------------------------------------------------------------ BRAND NAMES (Manufacturers) Aches-N-Pain [*] (Lederle) Advil [*] (Whitehall) Children's Advil (Whitehall) Genpril [*] (Goldline) Haltran [*] (Roberts) Ibuprin [*] (Thompson Medical) ibuprofen (various manufacturers) Medipren [*] (McNeil CPC) Midol 200 [*] (Glenbrook) Motrin (Upjohn) Motrin IB [*] (Upjohn) Nuprin [*] (Bristol-Myers) Pamprin-IB [*] (Chattem) PediaProfen (McNeil CPC) Rufen (Boots) Trendar [*] (Whitehall) * Available over-the-counter (without a prescription) as 200-mg tablets. TYPE OF DRUG Nonsteroidal anti-inflammatory analgesic INGREDIENT ibuprofen DOSAGE FORMs Tablets (200 mg, 300 mg, 400 mg, 600 mg, and 800 mg) Oral suspension (100 mg per 5-ml spoonful) STORAGE Store in a tightly closed, light-resistant container at room temperature. This medication should never be frozen. USES Ibuprofen is used to treat the inflammation (pain, swelling, stiffness) of certain types of arthritis, gout, bursitis, and tendinitis. It is also used to treat painful menstruation. Ibuprofen has been shown to block production of certain body chemicals, called prostaglandins, that may trigger pain. TREATMENT You should take this medication on an empty stomach 30 to 60 minutes before meals or two hours after meals, so that it gets into your bloodstream quickly. However, to decrease stomach irritation, your doctor may want you to take the medication with food or antacids. The oral suspension form of this medication should be shaken well just before measuring each dose. The contents tend to settle on the bottom of the bottle, so it is necessary to shake the container to distribute the ingredients evenly and equalize the doses. Each dose of the oral syrup or oral suspension should be measured carefully with a specially designed 5-ml measuring spoon. An ordinary kitchen teaspoon is not accurate enough. If you are taking ibuprofen to relieve arthritis, you must take it regularly as directed by your doctor. It may take up to two weeks before you feel the full effects of this medication. Ibuprofen does not cure arthritis, but it will help to control the condition as long as you continue to take it. It is important to take ibuprofen on schedule and not to miss any doses. If you do miss a dose, take it as soon as possible, unless it is almost time for your next dose. In that case, don't take the missed dose at all; just return to your regular dosing schedule. Do not double the next dose. SIDE EFFECTS Minor. Bloating, constipation, diarrhea, difficulty in sleeping, dizziness, drowsiness, headache, heartburn, indigestion, light-headedness, loss of appetite, nausea, nervousness, soreness of the mouth, unusual sweating, or vomiting. As your body adjusts to the drug, these side effects should disappear. To relieve constipation, increase the amount of fiber in your diet (fresh fruits and vegetables, salads, bran, and whole-grain breads), exercise, and drink more water (unless your doctor directs you to do otherwise). If you become dizzy or light-headed, sit or lie down for a while; get up slowly from a sitting or reclining position, and be careful on stairs. Major. If any side effects are persistent or particularly bothersome, you should report them to your doctor. IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about bloody or black, tarry stools; blurred vision; confusion; depression; difficult or painful urination; palpitations; a problem with hearing; ringing or buzzing in your ears; skin rash, hives, or itching; stomach pain; swelling of the feet; tightness in the chest; unexplained sore throat and fever; unusual bleeding or bruising; unusual fatigue or weakness; unusual weight gain; wheezing or difficulty in breathing; or yellowing of the eyes or skin. INTERACTIONS Ibuprofen interacts with several other types of medications: 1. Anticoagulants (blood thinners, such as warfarin) can lead to an increase in bleeding complications. 2. Aspirin, other salicylates, and other anti-inflammatory medications can increase stomach irritation. Aspirin may also decrease the effectiveness of ibuprofen. 3. Ibuprofen can interact with diuretics (water pills). 4. Probenecid may increase blood levels of ibuprofen, which may increase the risk of side effects. 5. The action of beta blockers may be decreased by this drug. BE SURE TO TELL YOUR DOCTOR about any medications you are currently taking, especially any listed above. WARNINGS * Before you start to take this medication, it is important to tell your doctor if you have ever had unusual or allergic reactions to ibuprofen, or to any of the other chemically related drugs (aspirin, other salicylates, diclofenac, diflunisal, fenoprofen, flurbiprofen, indomethacin, ketoprofen, meclofenamate, mefenamic acid, naproxen, oxyphenbutazone, phenylbutazone, piroxicam, sulindac, or tolmetin). * Tell your doctor if you now have or if you have ever had bleeding problems, colitis, stomach ulcers or other stomach problems, epilepsy, heart disease, high blood pressure, asthma, kidney disease, liver disease, mental illness, or Parkinson's disease. * If ibuprofen makes you dizzy or drowsy, do not take part in any activity that requires alertness. * Because this drug can prolong bleeding time, tell your doctor or dentist you are taking this drug before having surgery or other medical or dental treatment. * Stomach problems are more likely to occur if you take aspirin regularly or drink alcohol while being treated with this medication. These should, therefore, be avoided (unless your doctor directs you to do otherwise). * The elderly may be at increased risk for experiencing side effects of this drug. * Be sure to tell your doctor if you are pregnant. This type of medication can cause unwanted effects to the heart or blood flow of the fetus. Studies in animals have also shown that this type of medicine, if taken late in pregnancy, may increase the length of pregnancy, prolong labor, or cause other problems during delivery. Also, tell your doctor if you are breast-feeding an infant. Small amounts of ibuprofen can pass into breast milk. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.