$Unique_ID{BRK03162} $Pretitle{} $Title{flurandrenolide (topical)} $Subject{Cordran SP Dista Adrenocorticosteroid hormone flurandrenolide cortisone-like skin inflammation redness swelling itching discomfort dermatitis eczema poison ivy} $Volume{} $Log{} Copyright (C) 1993 Publications International, Ltd. flurandrenolide (topical) ------------------------------------------------------------------------------ BRAND NAMES (Manufacturers) Cordran (Dista) Cordran SP (Dista) flurandrenolide (various manufacturers) TYPE OF DRUG Adrenocorticosteroid hormone INGREDIENT flurandrenolide DOSAGE FORMS Ointment (0.025% and 0.05%) Cream (0.025% and 0.05%) Lotion (0.05%) Tape (4 mcg per square centimeter of tape) STORAGE Flurandrenolide ointment, cream, lotion, and tape should be stored at room temperature in tightly closed containers. This medication should never be frozen. USES Your adrenal glands naturally produce certain cortisone-like chemicals. These chemicals are involved in various regulatory processes in the body (such as those involving fluid balance, temperature, and reaction to inflammation). Flurandrenolide belongs to a group of drugs known as adrenocorticosteroids (or cortisone-like medications). It is used to relieve the skin inflammation (redness, swelling, itching, and discomfort) associated with conditions such as dermatitis, eczema, and poison ivy. How this drug acts to relieve these disorders is not completely understood. TREATMENT Before applying this medication, wash your hands. Then, unless your doctor gives you different instructions, gently wash the area of the skin where the medication is to be applied. With a clean towel, pat the area almost dry; it should be slightly damp when you put the medicine on. If you are using the lotion form of this medication, shake the bottle well before pouring out the medicine. The contents tend to settle on the bottom of the bottle, so it is necessary to shake the container to distribute the ingredients evenly and equalize the doses. Apply a small amount of the medication to the affected area in a thin layer. Do not bandage the area unless your doctor tells you to do so. If you are to apply an occlusive dressing (like kitchen plastic wrap), be sure you understand the instructions. When using the tape form of this medication, dry the skin thoroughly before applying the tape. Remove the tape from the package and cut a piece slightly larger than the area to be covered. Round off the corners. Pull the white paper from the transparent tape (be careful that the tape does not stick to itself). Press the tape into place, keeping the skin smooth. If ends of the tape loosen, they may be trimmed off and replaced with fresh tape. The tape should be cut, never torn. If you miss a dose of this medication, apply the dose as soon as possible, unless it is almost time for the next application. In that case, do not apply the missed dose; just return to your regular schedule. Do not put twice as much of the medication on your skin at the next application. SIDE EFFECTS Minor. Acne, burning sensation, itching, rash, or skin dryness. If the affected area is extremely dry or scaling, the skin may be moistened before applying the medication by soaking in water or by applying water with a clean cloth. The ointment form is probably better for dry skin. A mild, temporary stinging sensation may occur after this medication is applied. If this persists, contact your doctor. Major. Tell your doctor about any side effects that are persistent or particularly bothersome. IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about blistering, increased hair growth, irritation of the affected area, loss of skin color, secondary infection in the area being treated, or thinning of the skin with easy bruising. INTERACTIONS This medication does not interact with any other medications as long as it is used according to directions. WARNINGS * Tell your doctor about unusual or allergic reactions you have had to medications, especially to flurandrenolide or any other adrenocorticosteroid (such as amcinonide, betamethasone, clocortolone, cortisone, desonide, desoximetasone, dexamethasone, diflorasone, flumethasone, fluocinolone, fluocinonide, fluorometholone, halcinonide, hydrocortisone, methylprednisolone, paramethasone, prednisolone, prednisone, and triamcinolone). * Tell your doctor if you now have or if you have ever had blood vessel disease, chicken pox, diabetes mellitus, fungal infection, peptic ulcers, shingles, tuberculosis, tuberculosis of the skin, vaccinia, or any other type of infection, especially at the site currently being treated. * If irritation develops while using this drug, immediately discontinue its use and notify your doctor. * This product is not for use in the eyes or mucous membranes; contact may result in side effects. * Do not use this product with an occlusive wrap unless your doctor directs you to do so. Systemic absorption of this drug is increased if extensive areas of the body are treated, particularly if occlusive bandages are used. If it is necessary for you to use this drug under a wrap, follow your doctor's instructions exactly; do not leave the wrap in place longer than specified. * If you are using this medication on a child's diaper area, do not put tightfitting diapers or plastic pants on the child. This could lead to increased systemic absorption of the drug and a possible increase in side effects. * Be sure to tell your doctor if you are pregnant. If large amounts of this drug are applied for prolonged periods, some of it will be absorbed and may cross the placenta. Although studies in humans have not been conducted, birth defects have been observed in the offspring of animals that were given large oral doses of this type of drug during pregnancy. Also, tell your doctor if you are breastfeeding an infant. If absorbed through the skin, small amounts of flurandrenolide pass into breast milk and may cause decreased growth or a decrease in natural adrenocorticosteroid hormone production in the nursing infant. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.