$Unique_ID{BRK03135} $Pretitle{} $Title{dipyridamole} $Subject{Persantine Boehringer Ingelheim Pyridamole Major Antianginal dipyridamole chronic chest pain angina heart disease blood vessels oxygen muscle blood clot formation artificial heart valves} $Volume{} $Log{} Copyright (C) 1993 Publications International, Ltd. dipyridamole ------------------------------------------------------------------------------ BRAND NAMES (Manufacturers) dipyridamole (various manufacturers) Persantine (Boehringer Ingelheim) Pyridamole (Major) TYPE OF DRUG Antianginal INGREDIENT dipyridamole DOSAGE FORM Tablets (25 mg, 50 mg, and 75 mg) STORAGE Store at room temperature in a tightly closed container. USES Dipyridamole is used to prevent chronic chest pain (angina) due to heart disease. It relieves chest pain by dilating the blood vessels of the heart and providing more oxygen to the heart muscle. Dipyridamole is also used to prevent blood clot formation, especially in patients who have artificial heart valves. TREATMENT You should take this medication on an empty stomach with a full glass of water one hour before or two hours after a meal. If this drug upsets your stomach, check with your doctor to see if you can take it with food. The full benefits of this medication may not become apparent for up to two to three months. If you miss a dose of this medication, take the missed dose as soon as possible, unless it is within four hours of your next scheduled dose. In that case, do not take the missed dose at all; just return to your regular dosing schedule. Do not double the next dose. SIDE EFFECTS Minor. Dizziness, fatigue, flushing, headache, nausea, stomach cramps, or weakness. These side effects should disappear as your body adjusts to the medication. To avoid dizziness or light-headedness when you stand, contract and relax the muscles of your legs for a few moments before rising. Do this by pushing one foot against the floor while raising the other foot slightly, alternating feet so that you are "pumping" your legs in a pedaling motion. Major. Tell your doctor about any side effects that are persistent or particularly bothersome. IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about fainting, skin rash, or a worsening of your chest pain. INTERACTIONS Dipyridamole should not interact with other medications if it is used according to directions. WARNINGS * Tell your doctor about unusual or allergic reactions you have had to any medications, especially to dipyridamole. * Tell your doctor if you have ever had low blood pressure. * The effectiveness of dipyridamole in controlling chronic angina is controversial. This drug is more frequently prescribed to prevent blood clot formation, although use of dipyridamole for this purpose has not yet been approved by the Food and Drug Administration (FDA). * This drug does not stop chest pain from angina that has already begun. It is used only to prevent such pain * If this drug makes you dizzy, do not take part in any activity that requires alertness. * Before having any surgery or other medical or dental treatment, be sure to tell your doctor or dentist that you are taking this medication. * Be sure to tell your doctor if you are pregnant. Although this drug appears to be safe, extensive studies in humans during pregnancy have not been conducted. Also, tell your doctor if you are breast-feeding an infant. Small amounts of dipyridamole pass into breast milk. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.