$Unique_ID{BRK03105} $Pretitle{} $Title{codeine and iodinated glycerol combination} $Subject{Iophen-C Iotuss Muro Par Glycerol C ParTussi-Organidin Wallace Tussi-R-Gen Goldline Cough suppressant expectorant codeine iodinated glycerol coughs colds infection inflammation upper respiratory tract bronchial narcotic cough center brain} $Volume{} $Log{} Copyright (C) 1993 Publications International, Ltd. codeine and iodinated glycerol combination ------------------------------------------------------------------------------ BRAND NAMES (Manufacturers) Iophen-C (various manufacturers) Iotuss (Muro) Par Glycerol C (Par) Tussi-Organidin (Wallace) Tussi-R-Gen (Goldline) TYPE OF DRUG Cough suppressant and expectorant combination INGREDIENT codeine and iodinated glycerol DOSAGE FORM Oral liquid (10 mg codeine and 30 mg iodinated glycerol per 5-ml spoonful) STORAGE Codeine and iodinated glycerol combination should be stored at room temperature in a tightly closed container. Avoid exposure of this medication to high temperatures. USES This drug is used to relieve coughs due to colds or infection or inflammation of the upper respiratory tract. Iodinated glycerol is an expectorant, which loosens bronchial secretions. Codeine is a narcotic cough suppressant, which acts on the cough center in the brain. TREATMENT You can take codeine and iodinated glycerol combination on an empty stomach or, to avoid stomach irritation, with food or milk (as directed by your doctor). Each dose should be measured carefully with a specially designed 5-ml measuring spoon. To help loosen the mucus in the bronchi, you should drink a glass of water after each dose. If you miss a dose of this medication, take the missed one as soon as possible, unless it is almost time for the next dose. In that case, do not take the missed dose at all; just return to your regular dosing schedule. Do not double the next dose. SIDE EFFECTS Minor. Constipation, dizziness, drowsiness, nausea, restlessness, stomach upset, vomiting, or weakness. These side effects should disappear as your body adjusts to the medication. If you feel dizzy, sit or lie down for a while; get up slowly from a sitting or reclining position, and be careful on stairs. To relieve constipation, increase the amount of fiber in your diet (fresh fruits and vegetables, salads, bran, and whole-grain breads), exercise, and drink more water (unless your doctor directs you to do otherwise). Major. Tell your doctor about any side effects that are persistent or particularly bothersome. IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about blurred vision; cold, clammy skin; confusion; difficulty in breathing; fainting; skin rash; or swollen lymph nodes. INTERACTIONS This drug can interact with other types of drugs: 1. Concurrent use with other central nervous system depressants (such as alcohol, barbiturates, benzodiazepine tranquilizers, muscle relaxants, other narcotics, pain medications, phenothiazine tranquilizers, and sleeping medications) or with tricyclic antidepressants can lead to extreme drowsiness. 2. Use of a monoamine oxidase (MAO) inhibitor within 14 days of use of codeine and iodinated glycerol combination can lead to serious side effects. 3. The iodine component of iodinated glycerol can increase the side effects of lithium on the thyroid gland. It can also increase the effects of antithyroid medications. 4. Cimetidine combined with this medication can cause confusion, disorientation, and shortness of breath. BE SURE TO TELL YOUR DOCTOR about any medications you are currently taking. WARNINGS * Tell your doctor about unusual or allergic reactions you have had to any medications, especially to codeine, or to other narcotics (such as hydrocodone, hydromorphone, meperidine, methadone, opium, oxycodone, propoxyphene, and pentazocine), or to iodinated glycerol, iodine, or iodine-containing dyes. * Before starting to take this medication, be sure to tell your doctor if you now have or if you have ever had acne, asthma, brain disease, cystic fibrosis, gallstones or gallbladder disease, gastrointestinal diseases, heart disease, kidney disease, liver disease, lung disease, mental disorders, enlarged prostate gland, or thyroid disease. * If this drug makes you dizzy or drowsy, do not take part in activities that require alertness, such as driving a car or operating potentially dangerous equipment. * While you are taking this medication, drink several glasses of water a day to help loosen bronchial secretions, unless your doctor directs you to do otherwise. * Because this product contains codeine, it has the potential for abuse and must be used with caution. Tolerance may develop quickly; you should not use it in higher doses, or for longer periods, than recommended by your doctor. If you have been taking it for longer than several weeks, do not stop taking it until you first check with your doctor. Stopping the drug abruptly can lead to a withdrawal reaction (body aches, diarrhea, gooseflesh, vomiting, restlessness, runny nose, sneezing, sweating, trembling, or excessive yawning). Your doctor may, therefore, want to reduce your dosage gradually. * Be sure to tell your doctor if you are pregnant. This medication should not be taken during pregnancy. Large amounts of codeine taken during pregnancy can lead to addiction in the developing fetus, resulting in withdrawal reactions in the newborn infant. Iodinated glycerol can cause goiter (an enlarged thyroid gland) in the developing fetus. Also, tell your doctor if you are breast-feeding an infant. Both codeine and iodinated glycerol can pass into the breast milk and cause side effects in the nursing infant. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.