$Unique_ID{BRK03080}
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$Title{chlorhexidine gluconate}
$Subject{Peridex Procter Gamble Oral rinse chlorhexidine gluconate salt
gingivitis inflammation gums bacteria dental plaque}
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Copyright (C) 1993 Publications International, Ltd.


chlorhexidine gluconate
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BRAND NAME (Manufacturer)

     Peridex (Procter & Gamble)

TYPE OF DRUG

     Oral rinse

INGREDIENT

     chlorhexidine as the gluconate salt

DOSAGE FORM

     solution (0.12%)

STORAGE

     This product should be stored at room temperature in a tightly closed,
light-resistant container.  Chlorhexidine gluconate solution should not be
frozen.

USES

     Chlorhexidine gluconate solution is prescribed by dentists for the
treatment of gingivitis.  Gingivitis is a medical term for inflammation of the
gums characterized by redness, swelling, and bleeding upon probing.  Although
it is unknown exactly how the product works, it is believed to eliminate
bacteria, which can cause dental plaque.  Dental plaque is one of several
causes of gingivitis.

TREATMENT

     Treatment with chlorhexidine gluconate solution should begin following a
thorough cleaning of your teeth by your dental practitioner.
     Measure 1/2 fluid ounce (as marked in the cap given with the product) of
chlorhexidine gluconate solution, and swish in the mouth for at least 30
seconds.  Do not dilute it in water or other liquids.  It should be used full
strength.  Chlorhexidine gluconate solution should be used after brushing.
     Do not swallow chlorhexidine gluconate solution following use.  It should
be expectorated (spit out) after rinsing the mouth.

SIDE EFFECTS

     Minor.

     Irritation of the inside of the mouth can occur following use of this
product.  In addition, some patients may experience temporary taste
disturbances.  However, there have been no permanent taste disturbances
reported with continued use of chlorhexidine.

     Major.

     Be sure to tell your dentist about any side effects that are persistent
or particularly bothersome.  IT IS ESPECIALLY IMPORTANT TO TELL YOUR DENTIST
about any inflammation and swelling of the parotid salivary gland.
     Chlorhexidine may cause staining of the teeth and tongue.  This staining
will be more noticeable in patients who have a heavy accumulation of plaque.
Usually, this staining is temporary and can be easily removed from most tooth
surfaces with dental cleaning.  Rarely, some persons, especially those with
plaque, will have permanent stains.

INTERACTIONS

     There do not appear to be any significant drug interactions with this
medication.  However, you should make sure your dentist knows about all the
medications you are taking.

WARNINGS

     * Tell your doctor about any reactions you have had to any drugs,
especially to chlorhexidine gluconate solution.
     * Chlorhexidine gluconate solution has not been fully evaluated in
children under the age of 18.  Therefore, the product should not be used by
children in this age group.
     * To determine the effectiveness of chlorhexidine use, it is advisable to
have dental checkups at least every six months.
     * Be sure to tell your dentist if you are pregnant or breast-feeding an
infant.  Scientific studies have not yet determined the effects of the
administration of chlorhexidine to pregnant or nursing women or their babies.
Therefore, use of this product during this time should be carefully
considered.

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The material contained here is "FOR INFORMATION ONLY" and should not replace
the counsel and advice of your personal physician.  Promptly consulting your
doctor is the best path to a quick and successful resolution of any medical
problem.