$Unique_ID{BRK02470} $Pretitle{} $Title{Is Progesterone Good Medicine for PMS?} $Subject{monthly progesterone medication premenstrual syndrome pms placebo ill defined symptom symptoms genitourinary behavior behaviors medicine medicines medications treatment treatments menstruate menstruation} $Volume{N-14,R-22} $Log{ The Menstrual Cycle*0009101.scf} Copyright (c) 1992,1993 Tribune Media Services, Inc. Is Progesterone Good Medicine for PMS? ------------------------------------------------------------------------------ QUESTION: I am one of those women who suffer each month from the problems that come with my monthly. I have tried most solutions, with only some help, but never with the relief I would like. One of my sisters claims the medication she received from her doctor, progesterone, helps relieve her symptoms. Do you think that this may be the medicine for me? ------------------------------------------------------------------------------ ANSWER: It may well be, if you think it is. That is not a very scientific answer but it accurately reflects the findings in a recent study of this question. Premenstrual syndrome (or PMS) consists of a wide variety of symptoms that accompany the menstrual period in many women. They include nervous tension, irritability, mood swings, fatigue, depression, cramps, breast tenderness and insomnia. These symptoms may affect different women in different ways and with differing intensity, and so the effect of any medication becomes a very subjective study. But when 168 women with PMS were followed in a clinical trial of progesterone suppositories at the University of Medicine School of Medicine, the results were a bit astonishing. The women taking the suppository with the active medication were no better off than those taking a suppository with a placebo. While that may not prove that progesterone is ineffective, it does demonstrate that it does not provide more relief than a placebo. It may also explain why your sister obtained her relief, and why I stated that it you believe it can help you, it may well do so. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.