$Unique_ID{BRK02469} $Pretitle{} $Title{Do Placebos Really Work?} $Subject{placebos effect mind inactive chemicals suggestibility ill defined symptom symptoms medication medications medicine medicines treatment treatments placebos mental emotional condition conditions sugar pill pills behavior behaviors} $Volume{N-23,R-23,E-23} $Log{} Copyright (c) 1992,1993 Tribune Media Services, Inc. Do Placebos Really Work? ------------------------------------------------------------------------------ QUESTION: I am mystified by the notion that any ordinary substance can work like medications in some people. I am referring to "placebos" and while watching an old rerun of MASH, the doctors actually seemed to stop pain in the patients with ordinary water injections. Could this really happen or is it another case of an overworked writer's imagination? ------------------------------------------------------------------------------ ANSWER: To a very great extent, you can be a believer of most of the incidents you have seen on MASH, and the episode you describe could most certainly have occurred. The "placebo effect" is a most intriguing one, for in many cases it seems as if the mind has exerted an effect on the body equal to that of an active medication. But such is the case, and many of the medical treatments prescribed by ancient physicians relied heavily on these mechanisms. How else can you explain the "beneficial" effects of such diverse things as purging, sweat therapy, leeches, cupping, and blood letting, applied to weakened and sick individuals? The scientific literature contains several articles which review this phenomenon, and which find that placebos may be effective from 30 to 40 percent of the time, even higher in some types of mild depression. Even in the clinical trials used to evaluate the effectiveness of new medications, patients who are in the control group, and are specifically given inactive chemicals, will also show improvements in the condition being tested in about 1/3 of the cases. Some of the reasons for these mysterious workings may be the desire of the patient to be a "good" patient and respond to the doctor's influence, the results of suggestibility, or a compelling desire to feel well. It is a difficult to measure these results with accuracy, but because of the tremendous positive results which may be seen, it is important that much more study be dedicated to finding the explanation for this amazing effect. The results of such investigations could lead to reducing the number of medications or doses of medications in use, with a similar reduction in unwanted side effects as well. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.