$Unique_ID{BRK01925} $Pretitle{} $Title{Cold Medications and an Enlarged Prostate} $Subject{Cold medicate medication Medications enlarge Enlarged Prostate preparation preparations urinate urination antihistamine antihistamines decongestant decongestants chemical chemicals histamine histamines muscle muscles bladder blood vessel vessels tissue tissues nose neck urine} $Volume{} $Log{ Benign Hypertrophy of the Prostate*0007602.scf} Copyright (c) 1993 Tribune Media Services, Inc. Cold Medications and an Enlarged Prostate ------------------------------------------------------------------------------ QUESTION: My friend, who is always complaining about his physical ailments, now tells me that his doctor won't let him take a simple cold pill because he has "prostate trouble". I let most of his stories go by without questioning, but this one seems a bit farfetched. Could you explain this or just debunk it if it proves to be foolish? ------------------------------------------------------------------------------ ANSWER: It does make sense and if you just check the label on some cold preparations, you will discover a warning concerning use by people with urination problems due to large prostates. Cold preparations often contain two different types of medications, antihistamines and decongestants. Antihistamines help to work against chemicals that result from an allergic reaction (histamines) but they also can relax the smooth muscles of the bladder, reducing their ability to empty the bladder. While decongestants help constrict the swollen blood vessels in the tissue lining the nose that result from a cold, these same chemicals act to tighten the muscles located at the exit of the bladder (bladder neck) that must open to allow the urine to pass out of the bladder. In the case of a man with an enlarged prostate, the speed of urine flow is reduced, as the prostate squeezes against the passage, reducing its size and capacity. The effects of the medication aggravate this condition. Men with prostate problems, however, may still use cold preparations by starting with a smaller dose, half the recommended dosage. If there is no worsening of symptoms, a full dose may be used for the few days necessary to relieve cold symptoms. If difficulty in urinating develops, the medication should be discontinued. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.