$Unique_ID{BRK01903} $Pretitle{} $Title{What is the "BUN"?} $Subject{BUN blood kidney kidneys urea nitrogen checkup checkups examine examination examinations creatinine uric acid renal artery urine chemical chemicals test tests tested testing urea-nitrogen} $Volume{} $Log{ Anatomy of the Kidney*0004801.scf Cross Section of a Kidney*0004901.scf Formation of Urine*0015901.scf Kidney Nephrons*0004902.scf} Copyright (c) 1993 Tribune Media Services, Inc. What is the "BUN"? ------------------------------------------------------------------------------ QUESTION: Every year my brother has to take a physical for the company he works for. In the report from the hospital it showed his "BUN" from the blood test was 25, and higher than normal. I know it has something to do with his kidneys, and that kidney problems put our father on a machine for the last year of his life. Can you give us more information? ------------------------------------------------------------------------------ ANSWER: Your past experiences with your father have left you with an understandable anxiety and concern for your brother, but the information contained in your letter is not as frightening as you now believe. To start with, a finding of 25 for the BUN (blood urea nitrogen) is at the upper end of the normal range. Most of the blood tests taken during annual checkups are "screening" examinations, and any abnormal result should be followed up by another, perhaps more specific analysis. One of the major functions of the kidney is to rid the body of waste products. These substances include urea, creatinine and uric acid. When the blood enters the kidney by way of the renal artery, these substances are filtered out of the blood, and are transferred into the urine. When the urine passes out of the body, these unwanted substance are carried right along. However, when the kidney is not properly doing its job, these undesirable chemicals are not removed from the blood, and when blood is examined, a higher amount than normal is detected. However, the presence of these additional quantities do not tell us just what is ailing the kidney, merely that all the waste has not been removed. It takes some additional testing of both urine and blood, as well as special x-ray techniques to narrow down the range of possible causes, until finally a diagnosis can be made, and treatment started. But you're a long way from there at present. The chances are very much in your favor, since the result of this original screening is still in normal range, that a repeat test will show a lower level of BUN. At the same time additional tests such as creatinine may reveal that, after all, your brother's kidneys are still working as they should. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.