$Unique_ID{BRK01593} $Pretitle{} $Title{Older People and Medicines} $Subject{medication aging health problems aged old elderly Older Medicines drug age drugs anticoagulants narcotics antihypertensives Barbiturates Antihistamines geriatric geriatrics medications Medicine anticoagulant narcotic Barbiturate Antihistamine pharmaceutical pharmaceuticals treatment treatments} $Volume{R-23,T-23} $Log{} Copyright (c) 1991-92,1993 Tribune Media Services, Inc. Older People and Medicines ------------------------------------------------------------------------------ QUESTION: I have noticed that my doctor seems more concerned about all my medicines than in my younger days. He has even changed the dose on some medicines I have taken for years. Is there any reason for all this checking? ------------------------------------------------------------------------------ ANSWER: Older people use more medicines than the younger ones, and they are also much more susceptible to drug reactions and interactions. Most drug studies are conducted among young and middle-aged persons, so drug problems are not always identified quickly in older people. For this reason and several others, caution is important. As we age, our bodies change. These changes affect the way drugs are absorbed and used in our bodies. For instance, the older adult has a slower blood flow to the kidneys. This changes the rate a drug is excreted from the body. If the drug stays in the body for a longer period of time than expected, the dosage should be altered in order to avoid overloading the body with the drug. Distribution of the drug in the body's tissues may be altered in older people when blood flow slows down and other factors are changed. The older body typically has more fat than muscle, so fat-soluble drugs are not distributed as they would be in younger persons. Older people are usually more sensitive to anticoagulants, narcotics and antihypertensive drugs. Barbiturates may create more sedation than usual or may cause agitation. Antihistamines, including those found in over-the-counter preparations, may create more drowsiness. Older individuals also have more chronic health problems that can interfere with the actions of drugs, as well as taking the medicines as previously prescribed. Health problems become more complex, and this may require taking several different drugs prescribed by different doctors. The most important piece of advice I can give you is this: whenever medication is prescribed, be sure your doctor knows about every other medicine you are taking, whether by prescription from another physician or something purchased over the counter at your pharmacy. This will permit a careful choice of your new medicine, and help avoid drug interaction problems. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.