$Unique_ID{BRK01458} $Pretitle{} $Title{Can Antibiotics be Used to Cure a Stomach Ulcer} $Subject{ulcer cause treatment antibiotic digestive system antibiotics stomach peptic ulcers lining infection helicobacter pylori campylobacter h bacteria gastric digestion infections bacterial bacterium} $Volume{I-10,A-10} $Log{ Ulcers of the Digestive System*0005801.scf Peptic Ulcers*0005802.scf} Copyright (c) 1991-92,1993 Tribune Media Services, Inc. Can Antibiotics be Used to Cure a Stomach Ulcer ------------------------------------------------------------------------------ QUESTION: My sister reports that her husband is being treated with antibiotics to cure his stomach ulcer. It is certainly a new one on me, and we are wondering if she has it a bit mixed up, or if possibly the doctor isn't telling her the whole truth. Do you have any way of finding out about this treatment and telling us about it? We would be most grateful. ------------------------------------------------------------------------------ ANSWER: I think she has it right, and doubt that the doctor is holding back any bad news. Peptic ulcers (or stomach ulcers, if you will) are the result of one of three main factors: the use of medications which irritate the stomach lining, most noted with nonsteroidal anti-inflammatory agents (NSAIDs), cigarette smoking, and an infection caused by Helicobacter pylori (formerly known as Campylobacter pylori). There are some writers that insist that inheritance plays a role, or that life's stresses may also be a cause, but there is some controversy about this. The treatment of any illness depends upon its cause, so when the suspicion that H. pylori is present is proven to be true, antibiotics make an effective treatment. It is probable that the ulcer is an indirect result of the infection, and that the bacteria first interfere with some of the protective mechanisms of the stomach lining or actually damage the tissue before the ulcer develops. Some studies show that healing follows the use of antibiotics in such cases, while still other papers fail to demonstrate the same effect. There are no such doubts about the relationship between cigarettes, which damage the gastric lining, increase acid secretion and change the blood flow, and the development of a stomach ulcer. In addition, smoking slows up the healing process, and so patients who suffer an ulcer and are helped by treatment but continue smoking will find that the ulcer develops again and again. An ulcer may be treated with several medications now available, and a cure may be obtained in from 90 percent to 95 percent of patients who are adequately treated for a twelve week period. When ulcers do recur, an evaluation using an endoscope, which permits the physician to look into the stomach, is appropriate to determine the actual state of the disease. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.