$Unique_ID{BRK01348} $Pretitle{} $Title{What is Biliary Atresia?} $Subject{newborn biliary atresia ducts digestive system liver bile ducts intestines birth jaundiced abdomen swell kasai procedure procedures obstructed childbirth child baby babies newborns biles duct intestine abdominal swelling jaundice obstruction} $Volume{I-8,K-8} $Log{} Copyright (c) 1991-92,1993 Tribune Media Services, Inc. What is Biliary Atresia? ------------------------------------------------------------------------------ QUESTION: Although I have heard the term "biliary atresia" used in the paper in stories of babies requiring liver transplant, a situation in our own family now makes it important for me to understand the condition more fully. Please tell me what biliary atresia is, and how common it is? ------------------------------------------------------------------------------ ANSWER: About one infant in every 20,000 live births is affected by biliary atresia. This is a very serious disease in which the ducts that carry bile from the liver to the intestines become inflamed and obstructed. The first signs of biliary atresia appear just a few weeks after birth. The baby becomes jaundiced (its skin becomes yellow), its abdomen may swell due to an enlarged, hardened liver. Some infants become extremely itchy, uncomfortable and irritable. The cause of this often deadly disease is not yet known, although some researchers believe it may be due to a viral infection around the time of birth. Besides liver transplants, there is only one method of treatment that has been used with success in about 50 percent of cases. An operation called the Kasai procedure creates drainage of bile from the liver when the ducts have become obstructed. During the surgery, the damaged ducts are replaced with a length of the baby's own intestine, which forms a new duct. Unfortunately, this procedure only works if the damaged ducts were outside the liver. In many cases, the damaged ducts are inside the liver, and the only hope is a liver transplant. Such transplants are being perfected all the time. The rate of success is also improving because new drugs are being developed which help with the problem of organ rejection. Often, the most difficult problem to overcome is finding a donor organ that is acceptable. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.