$Unique_ID{BRK00946} $Pretitle{} $Title{How Could Cirrhosis of the Liver Develop So Quietly?} $Subject{cirrhosis liver jaundice Digestive appetite loss deficient nutrition nausea vomiting accumulation fluid toxic chemicals drugs drug reactions alcohol ascites} $Volume{I-8} $Log{ Cirrhosis of the Liver*0009700.tid Normal, Fatty and Cirrhotic Livers *0009701.scf What Causes Cirrhosis of the Liver*0009702.scf Symptoms of Cirrhosis of the Liver*0009703.scf} Copyright (c) 1991-92,1993 Tribune Media Services, Inc. How Could Cirrhosis of the Liver Develop So Quietly? ------------------------------------------------------------------------------ QUESTION: As if without warning, my brother has now been informed he is suffering from cirrhosis of the liver. However he has had no symptoms until just recently, when he visited his physician because of a weight loss. Do you feel the doctor was right in his diagnosis, and could you please explain how this disease developed so quietly? ------------------------------------------------------------------------------ ANSWER: It is difficult to comment on the correctness of the diagnosis without more information as to the findings of the examination and laboratory tests, but I can tell you that the condition of cirrhosis may develop over a period of time without many warning signs. Cirrhosis is the result of an ongoing situation during which the liver cells are damaged and replaced by scar tissue. As the amount of normal tissue decreases, the liver can not handle the many functions it must perform in the normal individual and the symptoms become apparent in a gradual fashion. Perhaps the first is a loss of appetite, which leads to deficient nutrition and a loss of weight, the situation you allude to in your question. The appetite loss can transform into actual nausea and then vomiting, further complicating the weight problem. A physical examination at this time can reveal a liver that is larger than normal, and close inspection of the skin may show the first signs of yellowing or "jaundice" which results when the liver can no longer remove certain bile pigments which are deposited in the skin. As the liver progresses along the course of the disease, ascites or accumulation of fluid in the abdomen occurs as blood flow through the liver is reduced. As the liver loses its abilities to function, these patients may experience an increased sensitivity to medications and drugs. All symptoms do not appear in all patients, and it is the task of both patient and physician to deal not only with these symptoms, but to discover the cause of the cirrhosis and remove it if possible. While there are many causes for liver disease that produce cirrhosis, including infections, exposure to toxic chemicals and drugs, as well as drug reactions, in many cases it is caused by chronic, prolonged and excessive use of alcohol. Such patients can be helped greatly by avoiding alcohol completely and consuming a nutritious balanced diet along with necessary vitamin supplements. This may be easier said than done, but a supportive, concerned family is a great resource for the patient. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.