$Unique_ID{BRK00929} $Pretitle{} $Title{Is There a New Drug to Help Bedwetters?} $Subject{bed wetting medication Genitourinary DDAVP Nasal Spray nocturnal diuresis hormone arginine vasopressin medications Drug Drugs antidiuretic hormones urine production} $Volume{R-16} $Log{} Copyright (c) 1991-92,1993 Tribune Media Services, Inc. Is There a New Drug to Help Bedwetters? ------------------------------------------------------------------------------ QUESTION: My girlfriend knows of the troubles I am having with my youngster, so when she saw a report about a new drug to help bedwetters she called me. However, I have been unable to find anything out from my local TV station, and all I know about the medicine is that it is a nasal spray. Is this enough for you to be able to provide me the information that could help solve our problem? ------------------------------------------------------------------------------ ANSWER: Your information is correct and certainly enough for me to point you in the right direction. After all, there are not many new drugs for this problem which come in the form of a nasal spray. The new medication is called DDAVP Nasal Spray, marketed by Rorer Pharmaceuticals and just recently approved by the Food and Drug Administration. Many children who do not respond to the many existing treatments for bed wetting at night (medical term: nocturnal diuresis) were found to lack normal levels of a hormone called arginine vasopressin. This chemical, which functions as an antidiuretic hormone, diminishes the production of urine, particularly at night. The lack of this hormone is thought to be the cause of many cases of bed wetting. The new medicine is provided as a nasal spray which may make it a bit easier to give to children. The medication is sprayed into each nostril at bedtime. If the initial dose of 0.2 mL for patients 6 years old and above is ineffective the dose can be doubled. One recent study reported a 41% reduction in the number of "wet nights" with this treatment. Of course all of this should be under the care of your physician, for this medication is by prescription only. The medication comes in 5 mL vials which should be sufficient for one month of treatment. By the time you read this, I am sure your physician will have all the information on this new product and will be able to help you. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.