$Unique_ID{BRK00747} $Pretitle{} $Title{Is There Anyway to Dissolve Gall Stones?} $Subject{special procedure procedures gall stone stones cholecystectomy cholesterol ursodeoxycholic acid URSO bile acid Actigall medication medications surgeries operation operations surgery surgical lithotripsy sound shock waves gallstone gallstones} $Volume{P-9,R-9} $Log{} Copyright (c) 1991-92,1993 Tribune Media Services, Inc. Is There Anyway to Dissolve Gall Stones? ------------------------------------------------------------------------------ QUESTION: My husband was rushed to the hospital with what we thought was a heart attack. After undergoing all the tests we were told that he had a gall bladder attack. Is there anyway to dissolve gall stones, or is the only cure an operation to remove the gall bladder? Our doctor tells us that surgery isn't necessary. ------------------------------------------------------------------------------ ANSWER: Your doctor is very much up to date in suggesting an alternative therapy to surgery. Until just recently, cholecystectomy (surgical removal of the gall bladder) was the only choice and more than a half million operations were performed each year. But if the gallstones are composed of cholesterol, without calcifications, they may be dissolved by a medication that was recently approved called ursodeoxycholic acid (URSO). URSO is a naturally occurring bile acid, which is found in small amounts in human bile, but is now marketed in the United States under the brand name of Actigall. This treatment may be used in nonemergency patients who do not desire surgery, or who may be at high risk as a surgical patient. The medication can dissolve small stones (less than 20 mm in diameter) in from 30% to 80% of patients, but may take from 6-24 months to do so. When there is some reduction in size after 6 months, it is likely that the entire stone can be dissolved by continuing the treatment. The medication is taken orally in capsule form twice a day. Another technique still under investigation is called lithotripsy, a process which uses sound shock waves to fragment the stones into smaller pieces, followed by the oral medication to complete the process. While you are making your decision, keep your husband away from fatty foods, which can reduce the chances of recurrence of another painful attack. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.