$Unique_ID{BRK00739}
$Pretitle{}
$Title{Estrogen and Cholesterol Level}
$Subject{menopause heart attack estrogen osteoporosis Circulatory replacement
therapy ERT cardiovascular disease high-density lipoprotein HDL}
$Volume{R-22}
$Log{
Cholesterol*0002700.tid
HDL Transports Cholesterol Back to the Liver*0002702.scf
The Ovaries*0002909.scf}

Copyright (c) 1991-92,1993   Tribune Media Services, Inc.


Estrogen and Cholesterol Level


------------------------------------------------------------------------------

QUESTION:  I am a woman past menopause, and have been put on estrogen by my
doctor.  Although I was sure it was being prescribed to prevent osteoporosis,
I was informed that it would help with my cholesterol level, and protect me
against heart attack.  Would you comment on this, please?

------------------------------------------------------------------------------

ANSWER:  For a long time physicians have been aware that prior to menopause
heart attacks were rare in women.  However, once past menopause, and in the 6
to 10 years that follow, the chance of heart attack in women gradually
approaches that of men.  Now researchers are saying the most important benefit
of estrogen replacement therapy (ERT) is protection against cardiovascular
disease and heart attack.  The risk of death from cardiovascular disease in
women on ERT is but a third of that of women who do not take estrogen.  Women
on ERT have higher levels of high-density lipoprotein (HDL, frequently
referred to as the "good" cholesterol) than postmenopausal women who on not on
this therapy.  However this beneficial effect disappears when the therapy is
discontinued.  There is still some controversy as to whether this therapy
should be combined with the use of another female hormone, progesterone, or
whether the therapy may be used in women with the history of blood clots
(thrombophlebitis, for example) or in women with fibrocystic breast disease.
There is no question about its value in preventing osteoporosis, and the
serious fractures that may result from that disease.

----------------

The material contained here is "FOR INFORMATION ONLY" and should not replace
the counsel and advice of your personal physician.  Promptly consulting your
doctor is the best path to a quick and successful resolution of any medical
problem.