$Unique_ID{BRK00678} $Pretitle{} $Title{Is a Good Night's Sleep Really Essential to Good Health?} $Subject{sleep health healing immune immunity lifestyle lifestyles muramyl peptide interleukin-1 deprivation irritability fatigue remembering coordination visual tactile hallucinations hallucination illusion illusions REM rapid eye movement} $Volume{U-23} $Log{} Copyright (c) 1991-92,1993 Tribune Media Services, Inc. Is a Good Night's Sleep Really Essential to Good Health? ------------------------------------------------------------------------------ QUESTION: Although my wife and I have very different sleep habits we both seem to be doing fine. However she sleeps for eight to ten hours each night, and has a good sleep. I only sleep for about four hours, it seems. We would like to know if is it true that a good night's sleep is really essential to good health? ------------------------------------------------------------------------------ ANSWER: A good night's sleep, one that is restful and calm, is high on the list of priorities of many readers, and so your question is an interesting one. More and more researchers are finding that a good night's sleep is actually very important in fighting disease. While there is a great variety in actual sleep requirements from individual to individual, most doctors feel 6 to 9 hours of total sleep in a 24-hour period is the proper amount for adults. Many aspects of sleep remain a mystery to researchers. Some even used to wonder if sleep was necessary at all. Recent research, however, has shown a link between sleep and the immune system. In experiments at the University of Chicago, white rats deprived of sleep died in an average of 19 days. During the deprivation period, the rats developed brown fur and ulcers of the paws and tail. In 1980, researchers John Pappenheimer, James Kreuger and Manfred Karnovsky isolated the chemical that induces sleep, muramyl peptide. This is a chemical known to activate cells called macrophages, which rush to sites of infection, where they remove bacteria and other foreign bodies from blood and tissues. Macrophages in turn make interleukin-1, a chemical which is known to influence temperature regulation and fever. Macrophages also signal to other disease fighting cells called lymphocytes, that they are needed at the site of an infection. Research into human sleep deprivation shows that it usually leads to irritability and fatigue, difficulty in concentrating and remembering, poor muscle coordination and visual or tactile hallucinations and illusions. Thus a bad night, with poor sleep patterns or little restful sleep, leads to a bad day, disrupting normal routines and reducing your efficiency. Scientists have also experimented with depriving people of one of the two states of sleep. They are known as REM sleep, or rapid eye movement sleep, in which dreaming occurs, and N-REM sleep, or nonrapid eye movement sleep. REM deprivation led to irritability, apathy, poor judgement, increased sensitivity to pain and a decrease in alertness. Many people who abuse sedatives, tranquilizers, antidepressants, and alcohol suffer many of the problems I've just mentioned, because these chemicals interfere with REM sleep. Most doctors agree that sleep helps people to recuperate from illness. It also has been theorized that REM sleep allows healing of mental activities and provides preparation for wakefulness. So, it seems that sleep is both a period of rest for the body and mind. There is still much more research necessary to unravel its many mysteries. Scientists hope to someday understand exactly how sleep works along with the immune system, and why sleep is part of the daily cycle of life. In your cases, since you state that you are both doing well, it is apparent that each of you is getting sufficient sleep, and so have little to worry about. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.