$Unique_ID{BRK00632} $Pretitle{} $Title{Infertility Tests} $Subject{fertility testes sperm sex cryptorchidism Mumps orchitis inflammation semen azoospermia varicocele infertility infertile fertile sterile sterility} $Volume{K-15} $Log{} Copyright (c) 1991-92,1993 Tribune Media Services, Inc. Infertility Tests ------------------------------------------------------------------------------ QUESTION: We have tried unsuccessfully to have a child for 3 years now. I have gone through all the tests, and now my husband realizes that he too must be tested. What are the chances that the problem may be with him and how will they discover it? ------------------------------------------------------------------------------ ANSWER: Infertility affects 15% of marriages, and studies estimate that a "male factor" is responsible in one-third of these cases. Through careful, sympathetic evaluation, the underlying causes can often be pinpointed and corrected, leading to successful pregnancy for many of these couples. First, the doctor must gather a complete sexual history of the couple, noting any factors that may affect or inhibit pregnancy, such as the frequency of sex and its timing in relation to the menstrual cycle. Lubricants, douches or other substances used in conjunction with sex may have a spermicidal effect and be preventing the sperm from reaching the uterus. One factor that reduces fertility in the male is cryptorchidism--in childhood, the failure of one or both of the testes to descend into the scrotum. If this condition remains uncorrected past the age of 5, irreversible changes take place in the testes which reduce their fertility. Mumps orchitis, an inflammation of the testes, also negatively affects their reproductive ability; if both are infected, sterility may result. Miscellaneous infections, emotional or physical stress, certain medications and even the treatment of hernias can impair fertility. To get the complete picture, it is necessary for the doctor to examine the genitals, with an eye towards any physical abnormalities in the structure of the penis or the scrotum. Analysis of the semen itself yields the most important data regarding fertility. Since semen takes 75 days to develop, at least two samples should be taken at two to three-week intervals. The various characteristics of semen (volume, shape and their degree of movement) can vary tremendously between samples. Semen volume in an ejaculation is usually between one and a half and five milliliters, while the density of spermatozoa present should be above 20 million per milliliter. Their degree of movement, or motility, should be active in at least 60% of sperm observed under a microscope within two to three hours of the sample being taken. Oval sperm heads are considered normal in such an evaluation; large, small, tapering, duplicated and amorphous heads may also be present. Fertile semen contains 10% abnormal, and between 60 and 70% normal forms. These tests may reveal the presence of azoospermia--a deformation in the testes preventing the creation of healthy sperm; while patients testing abnormal in all these characteristics are likely to have varicocele--a collection of dilated veins in the spermatic cord, the most responsive to surgery. Hormones are less likely to play a role in infertility, but can be tested if semen analysis fails to yield answers. A biopsy of testicular tissue is reserved for isolated cases. In unraveling these questions, emotional support from the spouse and physician is critical in resolving the psychological and physical stress resulting from infertility. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.