$Unique_ID{BRK00476} $Pretitle{} $Title{Chicken Pox Infections During Pregnancy} $Subject{immunization pregnancy chickenpox chicken pox virus Pregnancy Infections infection virus varicella-zoster virus VZV immunity infection immune globulin vidarabine acyclovir} $Volume{K-0, A-0} $Log{} Copyright (c) 1991-92,1993 Tribune Media Services, Inc. Chicken Pox Infections During Pregnancy ------------------------------------------------------------------------------ QUESTION: I have just learned that I am pregnant and will soon be the mother of a much desired baby. I have no recollection of ever having chickenpox as a child, and my physician has warned me about the possible results of an infection now. I am really worried and wish there was something I could do, some test I could take to avoid any problems. Can you help me? ------------------------------------------------------------------------------ ANSWER: There are many problems that come along with a newborn, and by staying calm, many problems find solutions that are easier than first thought. Chickenpox is caused by a virus, the "varicella-zoster virus" (VZV), which is highly communicable. That probably explains why we find that between 85% to 95% of all young adults living in temperate climates have developed immunity to the infection. While a history of chickenpox is a reliable indication of immunity, 75% of adults who have no recollection of ever having had the disease also display this immunity. A history of shingles would also indicate that you have an immunity. Unfortunately the test that might predict your immunity to VZV is not sensitive enough to detect the small amounts that remain long after the acute infection. The fact is that the subject of the effect of a VZV infection on a pregnancy is still one of controversy in medicine. While many authors believe that real risks exist, others cite studies which do not show a larger number of adverse outcomes after infection. If they do occur, they don't happen in every case where the mother is infected, and they are less severe when they occur later in the pregnancy. Your best defense on behalf of the baby is to stay away from any possibility of contact with individuals with either chickenpox or shingles. Should you be exposed to the infection, more than just a casual or brief contact, your physician might consider the use of varicella-zoster immune globulin, that could prevent or reduce the severity of your infection. If you did develop a severe case, treatment with either vidarabine or acyclovir can be used without danger to the baby. It would seem that both your risks and those of the infant are quite small, and that there are effective measures that may be taken should circumstances warrant such action. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.