$Unique_ID{BRK00407} $Pretitle{} $Title{What Causes Morphea and Will it Turn to Cancer?} $Subject{circumscribed scleroderma morphea Ill Defined Symptoms symptom Rare Diseases disease Skin Subcutaneous Tissue headaches arthritic pain collagen dermis layer edematous swells swelling lump lumps trauma pregnancy menopause headache} $Volume{N-20,L-20} $Log{ Anatomy of the Skin*0006701.scf} Copyright (c) 1991-92,1993 Tribune Media Services, Inc. What Causes Morphea and Will it Turn to Cancer? ------------------------------------------------------------------------------ QUESTION: My son was recently diagnosed as having a rare skin disease called Morphea. He has three lumps on his back now. Can you tell me what causes them, and whether this will ever turn to cancer? ------------------------------------------------------------------------------ ANSWER: Morphea, known also as circumscribed scleroderma, was first described by Dr. C.H. Fagge, in the Guy's Hospital Report, in 1868. It is not a disease one sees every day, and is usually observed more frequently in women than men. With an onset between the ages of 20 to 40, it may be accompanied by headaches and arthritic type pain. Actually it is a disease that attacks the collagen elements of the dermis layer of the skin. The area becomes filled with fluid (edematous) and swells, causing the lumps you have observed. It then proceeds to form scar like tissue, making the skin feel hard. There are five different varieties that are recognized, each a bit different in the way it looks, and the areas of the body it affects. No clear cause has been discovered, although its beginnings may be associated with trauma to the skin, pregnancy or menopause. Usually no treatment is indicated, but in serious cases, the affected areas may be injected with corticosteroids, cortisone-like medication. If the scars interfere with necessary functions, surgery may be performed to remove them. I found no mention of this condition becoming cancerous in the material I read, but am pleased to report that several types of morphea may improve spontaneously after a three to five year period. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.