$Unique_ID{BRK00295} $Pretitle{} $Title{What are the Symptoms of Lead Poisoning?} $Subject{lead water poisoning poison poisons headaches headache colicky vomiting constipation loss appetite metallic taste changes gait seizure coma blood test tests concentration-PbB sensitive screening white cell cells basophilic stippling chelating agent bind metals toxic kidneys urine paint contaminated foods folk medicines plumbing} $Volume{O-7} $Log{ Blood Cell Count Usage in Diagnosis*0002102.scf Eosinophil and Basophil (White) Blood Cells*0002106.scf} Copyright (c) 1991-92,1993 Tribune Media Services, Inc. What are the Symptoms of Lead Poisoning? ------------------------------------------------------------------------------ QUESTION: We are terribly worried, as recently the community was put on notice about lead in our water and the damage it can do to your body. Can you discuss lead poisoning so we will all be able to recognize its symptoms? ------------------------------------------------------------------------------ ANSWER: I can and will, but recognizing the symptoms of lead poisoning is not always easy, and can easily be confused with other ailments. In the adult, the symptoms are slow to develop and do so over a period of several weeks. They can include headache, vague abdominal discomfort which increases and develops into colicky abdominal pain, accompanied by vomiting and constipation. Headache is frequent, as well as loss of appetite, and frequently a metallic taste in the mouth. The appearance of symptoms in children is much more rapid and acute, developing over a period of 4 to 5 days with persistent and forceful vomiting, changes in gait, changes in consciousness leading to seizure, finally to coma. When exposure to lead is halted, the symptoms may disappear without treatment, only to return if exposure to lead recurs. Specific tests exist to determine the amount of lead in the blood (blood lead concentration-PbB) as well as sensitive screening test which are particularly useful in testing at-risk children. Ordinary blood counts can reveal the disease when the the white cells display a picture called "basophilic stippling". Even x-rays are helpful as they reveal lead in the bones. Treatment for lead intoxication involves the use of chelating agents. A chelating agent has the ability to bind metals to it, eliminating its toxic effects and clearing the lead from the body, through the kidneys in the urine. The use of such powerful chemicals requires skill and careful attention to the function of the kidneys during the process. For this reason chelating agents are never given as preventive medication to patients without symptoms. Of course, here as in all medicine, preventive effort should be begun, directed at eliminating the source of the lead, from paint, contaminated foods, folk medicines containing lead, burning lead painted wood, and water that has come into contact with lead plumbing. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.