$Unique_ID{BRK00156} $Pretitle{} $Title{Does Cholesterol Affect Women Differently than Men?} $Subject{cholesterol women Circulatory System cardiovascular disease heart menopause estrogen lipid lipoprotein diabetes mellitus triglyceride diseases diabetic blood fat circulation diabetics} $Volume{G-7} $Log{ How Cholesterol Levels Affect Arteries*0002701.scf HDL Transports Cholesterol Back to the Liver*0002702.scf Exercise Increases HDL*0002703.scf} Copyright (c) 1991-92,1993 Tribune Media Services, Inc. Does Cholesterol Affect Women Differently than Men? ------------------------------------------------------------------------------ QUESTION: My reading tells me there might be some differences in the way cholesterol affects men and women. Is it true that high cholesterol has a different meaning in women? ------------------------------------------------------------------------------ ANSWER: High cholesterol, which can ultimately lead to cardiovascular disease, is a health concern for both men and women. But as your question suggests, there are differences in the way it affects the two sexes. To begin with, heart disease usually affects women at a much later age than men--frequently after the age of sixty-six. Since the incidence of heart disease remains low in women until after menopause, it is believed that estrogen has a protective influence for women. This is further substantiated by the fact that lipid and lipoprotein levels are similar in boys and girls until puberty. At that point, apparently due to hormonal changes, levels of low and high density lipoprotein cholesterol change, decreasing cardiovascular risk in women and increasing it in men. High density levels, found in women throughout life, are known to remove cholesterol from peripheral areas of the body, including the arterial wall. Therefore, women are usually at a much lower risk for complications than men. After menopause, however, low density levels of lipoprotein cholesterol rise and actually surpass those in men of similar age. At that point, women become as likely a target as men for cardiovascular disease. Women who have diabetes, high levels of triglyceride (a type of fat), or a history of heart disease in their family can be at high risk for problems throughout their life; and in such cases, comprehensive testing should be performed on a routine basis. Despite the protective influence of estrogen, we must keep in mind that heart disease is the most common cause of death for both men and women, and for this reason, monitoring cholesterol levels in female patients should be treated just as seriously as it is for men. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.