$Unique_ID{BRK00101} $Pretitle{} $Title{What Makes Artificial Sweeteners Sweet?} $Subject{artificial sweeteners sweet aspartame cyclamates saccharin sweeten nutritive nonnutritive Sugars glucose fructose sucrose lactose maltose honey maple syrup NutraSweet amino acids phenylalanine phenylketonuria sweetener Sugar community diet diets dieting dietary dieter dieters food foods drink drinks acid} $Volume{Q-26} $Log{} Copyright (c) 1991-92,1993 Tribune Media Services, Inc. What Makes Artificial Sweeteners Sweet? ------------------------------------------------------------------------------ QUESTION: What makes artificial sweeteners sweet? And after all the discussion in recent years about cyclamates and saccharin, can we be sure they're safe to use? ------------------------------------------------------------------------------ ANSWER: A variety of synthetic and natural substances are used to sweeten foods, and are classified as nutritive or nonnutritive, depending on whether they add calories to the diet or not. Sugars are the most common sweeteners, and are found widely in nature, including glucose, fructose (which together compromise sucrose--in granular form, the stuff you and I put on our corn flakes), lactose (present in milk), maltose, honey and maple syrup. Aspartame (well known by its NutraSweet trade name) is a nutritive (caloric) sugar made from two amino acids. While the equal of sucrose in calories, it is over 200 times sweeter; the tiny amount needed to sweeten any food is calorically insignificant. Saccharin, the most widely known nonnutritive sweetener, has been around since 1879, and is 300 times sweeter than sucrose. While a 1977 study that fed megadoses of the substance to laboratory rats prompted health warnings on saccharin-bearing products, to date no proof has been found that a normal level of saccharin consumption is dangerous. Possibly because of those health warnings (and because of a lack of any aftertaste), aspartame has replaced saccharin in a wide variety of sweetening applications. However, aspartame contains a chemical called phenylalanine, dangerous to individuals with the inherited disease phenylketonuria. Cyclamate sweeteners were not as lucky. Popular in the 1960's, cyclamates were removed from the market in 1969 after one test showed a possible cancer link. This link has never been confirmed, and cyclamates may one day return to the market in the U.S., joining the 40 countries around the world that approve their use. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.