$Unique_ID{BRK00085} $Pretitle{} $Title{What is the Drug that Makes Your Skin Look Younger?} $Subject{young skin treatment tretinoin Vitamin A acne facelift deaging wrinkling age spots spot precancerous treatments wrinkle wrinkles} $Volume{L-20} $Log{} Copyright (c) 1991-92,1993 Tribune Media Services, Inc. What is the Drug that Makes Your Skin Look Younger? ------------------------------------------------------------------------------ QUESTION: What is the drug that makes your skin look younger? ------------------------------------------------------------------------------ ANSWER: It's called tretinoin, a derivative of Vitamin A. Tretinoin has been used for several years to treat acne, and it is still only approved by the Food and Drug Administration for this purpose. This means that the FDA only recognizes its effectiveness and safety for the treatment of acne, because testing has only been done in this area. Doctors are prescribing it to help improve the texture and appearance of sun-damaged skin, but they are closely supervising its use. The drug is not without damaging and uncomfortable side effects, so it should be used only under a qualified doctor's close supervision. Some people are claiming the product produces a "chemical facelift," deaging the skin and reversing the damage done by years of sun exposure. The original study that used tretinoin to treat sun-damaged skin reported that the cream, when used over a 16-week period, reduced wrinkling, lightened age spots and improved skin tone and texture. Further study showed that the number of skin cells was increased, and that the "turnover" of the cells was speeded up, giving the appearance of more youthful skin. Besides the cosmetic benefits of tretinoin, the researchers found that it reversed certain precancerous changes in the skin. It will be especially interesting to learn how the product affects wound and burn healing. Studies are underway now to learn more about these applications. Anyone who uses tretinoin, whether for acne or to reverse skin changes that come with age and sun exposure, should be aware that it is a powerful drug. Tretinoin should be applied only as directed, which means to skin that has been washed clean with a mild soap then thoroughly dried. Wait 30 minutes, to be sure that no moisture remains on the skin. Apply the cream as prescribed. Be very cautious of sun exposure, because tretinoin makes the skin very susceptible to burning. During the first few weeks, skin will peel. This is expected. However, if an irritation develops, talk with your doctor. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.