$Unique_ID{BRK00066} $Pretitle{} $Title{Can Gastritis be Caused by Infection?} $Subject{gastritis ulcer infection infections cancer cancers Digestive System Gastric foods food mucosa mucosal lining viral virus viruses bacterial bacteria bacterium carcinoma gastrointestinal antrum duodenal ulcers C pylori Bismuth Pepto-Bismol} $Volume{I-10, A-10} $Log{} Copyright (c) 1991-92,1993 Tribune Media Services, Inc. Can Gastritis be Caused by Infection? ------------------------------------------------------------------------------ QUESTION: Can gastritis be caused by infection? I always thought it was from food. ------------------------------------------------------------------------------ ANSWER: Gastritis can actually be caused by a number of things. As you suggest, it can develop from eating foods that injure the mucosal lining of the stomach. It can also result from drug use, smoking, and alcohol which can damage and inflame the gastric mucosa. However, the condition can also be caused by factors totally unrelated to diet. The reflux of intestinal contents into the stomach has been a determined cause of gastritis. Immunologic and genetic factors are proven contributors as well. And, in answer to your question, gastritis can be the result of certain viral and bacterial infections. In simple terms, gastritis involves inflammation and the possible wearing away of gastric mucosa. It is frequently associated with ulcer disease, and in severe cases, with gastric carcinoma. Two main types exist: Type A, which involves the stomach and develops after age 50 in association with a type of anemia, and Type B, which involves the gastric antrum and is usually accompanied by gastric or duodenal ulcers. Addressing your concern on the link between infection and gastritis, it has been discovered that most patients suffering from Type B gastritis are infected with C pylori bacteria, leading experts to believe that C pylori is a major causative agent. When C pylori is treated, mucosal inflammation decreases and function improves. Since gastritis has long been an enigma as a disease, its association with C pylori has researchers hopeful that once a cure for C pylori infection is found, we will finally gain a handle on treating gastritis. Unfortunately, there is no reliable cure of C pylori infection available as yet. Bismuth compounds, such as Pepto-Bismol, suppress the infection and gastritis, but C pylori organisms reappear once the drug is discontinued. Moreover, there are many cases of C pylori infection where no gastritis is evident, implying that even if it plays an important contributing role in the development of gastritis, C pylori may not be the total answer in itself. In the meantime, extensive research is still being done to find ways to help patients suffering from gastritis. In cases where food or toxic agents are the cause, a controlled diet can offer relief, and a doctor's consultation is advised. Cures for more complicated gastric conditions will hopefully be available in the near future. ---------------- The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician. Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.