Glucosamine Provides Arthritis Relief
- A 1982 study by St. John hospital in Portugal showed that Glucosamine
significantly outperforms ibuprofen for reducing knee pain in patients
suffering from osteoarthritis.
Forty patients were treated using 1.5 grams of glucosamine sulfate or 1.2
grams of ibuprofen daily for an 8 week period. The ibuprofen group decreased
pain levels more quickly, but the glucosamine group showed the most improvement
over the entire 8 week period.
- A 1994 double blind placebo study in Milan, Italy showed glucosamine
sulfate to be more effective than placebo and equally effective as non-steroidal
anti-inflammatory drugs in relieving osteoarthritis symptoms. This study
of knee patients supports earlier results using glucosamine supplements
for pain and motion limitation.
- A 1981 study of 54 patients in Bangkok, Thailand showed that Glucosamine
reduced joint pain, accelerated recovery, and partially restored
articular function. Glucosamine injections for 5 weeks helped arthritis
patients decrease swelling and pain with no side effects. In addition,
the clinical recovery did not fade after treatment ended, but lasted another
4 weeks.
- A 1980 hospital study in Venice, Italy confirmed that both oral and
injectable glucosamine sulfate caused significant improvement in osteoarthritis.
Faster and greater improvement in articular function suggests "that
glucosamine sulfate should be considered for the basic therapy of primary
or secondary osteoarthritis."
- Another 1980 study in Milano, Italy showed oral glucosamine delivers
nearly twice the reduction of symptoms of osteoarthritis. 1.5 grams of
glucosamine sulfate were given daily for 30 days to patients who were scored
for articular pain, joint tenderness and swelling, and restriction of movement.
It was concluded that glucosamine sulfate tends to rebuild damaged cartilage,
thus restoring articular function.
- A 1991 study by the Dept. of Pathology at Thomas Jefferson University
using chick embryos showed D-Glucosamine hydrochloride to be as effective
as glucosamine sulfate. D-Glucosamine HCL was able to restore synthesis
of major proteoglycans with normal size chondroitin sulfate chains.
Glucosamine research
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