THREEDOM is a program for searching a database of 3-dimensional chemical structures to find those which have high similarity (in shape or electron charge distribution) to a target structure. It uses the "Icosahedral Matching Algorithm" for efficient alignment of structures. Its prime application is in the pharmaceutical and agrochemical fields in the search for "lead" compounds.
Peter Bladon
Interprobe Chemical Services
Gallowhill House, Larch Avenue
Kirkintilloch
Glasgow, SC G66 4HX
UK
44-141-578-1109
44-141-578-1109 (fax)
cbas25@strath.ac.uk
For applications in related solution areas, see the following indices: Chemical Information Database, Chemometrics, the developer index for Interprobe Chemical Services and the product category index for Chemistry, Biochem, Biotechnology.
THREEDOM is a Trademark of Interprobe Chemical Services