How do I get Queen Elizabeth and Drake to meet?

Hint 1 of 18:

Elizabeth will have to meet Drake in the left bedroom, since
Vettenmyer told Drake to go there.

Hint 2 of 18:

You'll have to know something about history to get through this one.

Hint 3 of 18:

Read your briefing papers to learn as much as you can about Elizabeth.

Hint 4 of 18:

The important thing here is to know why she's at war with Spain.

Hint 5 of 18:

She hates the Catholic Church, doesn't she?

Hint 6 of 18:

You have to visit Rome, 1519 AD, to finish this puzzle.

Hint 7 of 18:

You'll need the plaque from that timeplace.