Spybot-Search&Destroy supports the concept of basic skins, to adjust program colors to personal needs.

The Skin section will show you a list of available skins. Select one to preview it. The (very simple) preview will be displayed in the left part of the window, with some information below the list and the skin logo at the bottom of the page.

If you like the skin, press the Apply button.

You can find the skin settings by choosing Skins from the Settings section in the toolbar to the left.