Document 0746
 DOCN  M9480746
 TI    [Reflections on 10 years of medically induced abortions in
       Ille-et-Vilaine]
 DT    9410
 AU    Schneider S; Roussey M; Odent S; Debroise C; Poulain P; Jouan H; Milon
       J; Betremieux P; Journel H; Le Mee F; et al; Service de
       Pediatrie-Genetique Medicale, CHU Pontchaillou,; Rennes.
 SO    J Gynecol Obstet Biol Reprod (Paris). 1994;23(2):157-65. Unique
       Identifier : AIDSLINE MED/94315248
 AB    The medical files of 532 patients who underwent medically induced
       abortion over a 10-year period (1982-1991) in the French department of
       Ille-et-Vilaine were studied in order to evaluate the indications and
       outcomes. Among the patients, 358 resided in the department (67%).
       Comparatively with the number of births during the 10-year period, there
       was a relative increase in the number of medically induced abortions
       from 3.5/1000 to 5.5/1000. This parameter was taken into consideration
       for the interpretation of a parallel decrease in the perinatal mortality
       during the same period, from 5.9/1000 to 5.1/1000. There was a maternal
       indication in 91 cases which correspond to the former category of
       therapeutic induced abortions. There was a clear increase in 1991
       corresponding to abortions induced because of extremely premature
       rupture of the membranes which were formerly allowed to continue to dead
       births. Foetal indications were frequent: 441 cases (83%). Exogenous
       causes were lower (15.6%), particularly due to the disappearance of
       indications resulting from maternal irradiation. For indications related
       to infection, the vaccination against rubella and improved prenatal
       diagnosis resulted in the disappearance of rubella as an indication
       during the last three years of the study and a clear decrease in the
       number of toxoplasmosis indications. There were few indications due to
       maternal infection by human immunodeficiency virus (4 cases).
       Chromosomal abnormalities were the main cause of medically induced
       abortion among the foetal indications (27.7%).(ABSTRACT TRUNCATED AT 250
       WORDS)
 DE    Abnormalities/DIAGNOSIS/EPIDEMIOLOGY/PREVENTION & CONTROL  *Abortion,
       Induced/METHODS/STATISTICS & NUMER DATA/TRENDS  Adolescence  Adult
       Birth Rate  Chromosome Abnormalities/DIAGNOSIS/EPIDEMIOLOGY/PREVENTION &
       CONTROL  English Abstract  Female  Fetal Membranes, Premature
       Rupture/EPIDEMIOLOGY  France/EPIDEMIOLOGY  Hereditary
       Diseases/DIAGNOSIS/EPIDEMIOLOGY/PREVENTION & CONTROL  Human  Mass
       Screening  Maternal Age 35 and over  Middle Age  Pregnancy  Pregnancy
       Complications/DIAGNOSIS/EPIDEMIOLOGY  Residence Characteristics
       Retrospective Studies  Treatment Outcome  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).