Document 0719
 DOCN  M9480719
 TI    [A case of bronchiectasis accompanied by ulcerative colitis (UC) and
       HTLV-1 associated myelopathy (HAM)]
 DT    9410
 AU    Suzuki I; Watanabe N; Suzuki J; Yamaguchi E; Munakata M; Fujita M; First
       Department of Medicine, Hokkaido University School of; Medicine,
       Sapporo, Japan.
 SO    Nippon Kyobu Shikkan Gakkai Zasshi. 1994 Apr;32(4):358-63. Unique
       Identifier : AIDSLINE MED/94315794
 AB    We report a case of bronchiectasis with marked thickening of the
       respiratory tract wall occurring in a 37-year-old man with UC and HAM.
       He was diagnosed as UC at age 20. HTLV-1 was presumably transmitted to
       this patient by means of a blood transfusion he received at around age
       30. On admission, chest X-ray films, tomography and CT-scan revealed
       dilated lumens and thickened airway walls extending from the trachea to
       subsegmental bronchi. Pulmonary function tests showed hypoxemia and
       mixed ventilatory disturbance with a predominantly obstructive
       component. HAM was diagnosed on the basis of neurological examination
       and cerebrospinal fluid analysis. A biopsy specimen from the carinal
       mucosa showed marked T cell infiltration. In these T cells, we detected
       polyclonal integration of HTLV-1 proviral DNA. Some of the infiltrating
       T cells showed atypia. In recent times, respiratory diseases other than
       infiltration of adult T-cell leukemia cells or opportunistic infection
       have been reported in HTLV-1 carriers and new clinical entities
       designated as HABA (HTLV-1 associated bronchiolo-alveolar disorder) and
       HBA (HTLV-1 associated bronchopneumopathy) have been proposed. This case
       is classified among these new entities, in a broad sense, and is a rare
       case in that the respiratory disorder is apparently related to UC.
 DE    Adult  Bronchiectasis/*ETIOLOGY  Case Report  Colitis,
       Ulcerative/*COMPLICATIONS  English Abstract  Human  Male  Paraparesis,
       Tropical Spastic/*COMPLICATIONS  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).